Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | STS | P08842 | 1/20 | 0.44 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4371405 | 1.00 | ALDH1A1 (0.58) | ALDH1A1MAPTHTTNPC1MAPK1 | |
| SCHEMBL14342621 | 0.80 | L3MBTL1 (0.57) | ALDH1A1MAPTHTTNPC1MAPK1 | |
| SCHEMBL5521359 | 0.80 | L3MBTL1 (0.57) | ALDH1A1MAPTHTTNPC1MAPK1 | |
| SCHEMBL14978794 | 0.80 | L3MBTL1 (0.57) | ALDH1A1MAPTHTTNPC1MAPK1 | |
| SCHEMBL2709640 | 0.78 | ALDH1A1 (0.74) | ALDH1A1MAPTHTTNPC1MAPK1 | |
| SCHEMBL27022359 | 0.78 | RECQL (0.61) | ALDH1A1MAPTHTTNPC1MAPK1 | |
| SCHEMBL27093580 | 0.76 | CKS1B (0.48) | ALDH1A1MAPTHTTNPC1MAPK1 | |
| SCHEMBL24621773 | 0.75 | GPR119 (0.60) | ALDH1A1MAPTHTTNPC1MAPK1 | |
| SCHEMBL7476905 | 0.75 | ALDH1A1 (0.56) | ALDH1A1MAPTHTTNPC1MAPK1 | |
| SCHEMBL15270418 | 0.75 | ALDH1A1 (0.56) | ALDH1A1MAPTHTTNPC1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009012375-A2 | SQUARATE KINASE INHIBITORS | WYETH (US) | 2009-01-22 | — | — | WO | disclosed |