Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHUK | O15111 | 1/20 | 0.42 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.42 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | IDH1 | O75874 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 3/20 | 0.38 |
| ▸ | PPARA | Q07869 | 3/20 | 0.38 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | BCL2 | P10415 | 1/20 | 0.37 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | CTSG | P08311 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1201119 | 0.79 | DRD2 (0.43) | DRD2DRD4DRD3PPARGPPARA | |
| SCHEMBL2117943 | 0.77 | PPARG (0.40) | CHUKTXNRD1NOX4DRD2DRD4 | |
| SCHEMBL4247573 | 0.72 | HSD17B1 (0.54) | CHUKTXNRD1NOX4KMT2AALDH1A1 | |
| SCHEMBL28279483 | 0.72 | EGFR (0.43) | CHUKTXNRD1NOX4DRD2DRD4 | |
| SCHEMBL4812206 | 0.72 | DRD2 (0.38) | DRD2DRD4DRD3PPARGPPARA | |
| SCHEMBL2117407 | 0.71 | DRD2 (0.43) | DRD2DRD4DRD3PPARGPPARA | |
| SCHEMBL29171105 | 0.71 | CALM1 (0.42) | DRD2DRD4DRD3KMT2ATSHR | |
| SCHEMBL2262370 | 0.69 | ENPP3 (0.44) | GAABRD4ALDH1A1 | |
| SCHEMBL23023619 | 0.69 | CES1 (0.43) | IDH1BRD4 | |
| SCHEMBL28226780 | 0.69 | BRD4 (0.43) | IDH1PPARGPPARABRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009066060-A2 | 4-SUBSTITUTED-6-ISOPROPYL-BENZENE-1,3-DIOL COMPOUNDS AND THEIR USE | TOPOTARGET A/S (DK) | 2009-05-28 | — | — | WO | disclosed |