SCHEMBL4543403

SCHEMBL4543403

COC(=O)C(C#N)=C(C)c1ccccc1OC

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTSD P07339 1/20 0.47
STAT3 P40763 1/20 0.45
HPGD P15428 3/20 0.45
NPC1 O15118 3/20 0.44
RAB9A P51151 2/20 0.44
CYP19A1 P11511 1/20 0.44
ADORA2A P29274 1/20 0.44
ADORA2B P29275 1/20 0.44
ADORA1 P30542 1/20 0.44
KCNK3 O14649 1/20 0.43
KCNK9 Q9NPC2 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
MAPK1 P28482 2/20 0.43
GAA P10253 1/20 0.42
MAPT P10636 1/20 0.42
TSHR P16473 1/20 0.42
HSD17B10 Q99714 1/20 0.42
RXFP1 Q9HBX9 1/20 0.42
TP53 P04637 1/20 0.42
GLA P06280 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7792874 0.86 LMNA (0.49) CTSDSTAT3HPGDNPC1RAB9A
SCHEMBL1554326 0.86 SMN1; SMN2 (0.52) CTSDHPGDNPC1RAB9ACYP19A1
SCHEMBL1554328 0.86 SMN1; SMN2 (0.52) CTSDHPGDNPC1RAB9ACYP19A1
SCHEMBL1633966 0.83 HPGD (0.44) HPGDNPC1RAB9AADORA2AADORA2B
SCHEMBL1633968 0.83 HPGD (0.44) HPGDNPC1RAB9AADORA2AADORA2B
SCHEMBL7651534 0.82 ALDH1A1 (0.48) CTSDNPC1RAB9ACYP19A1SMN1; SMN2
SCHEMBL18078309 0.78 ALDH1A1 (0.46) HPGDNPC1RAB9ACYP19A1SMN1; SMN2
SCHEMBL18078308 0.78 ALDH1A1 (0.46) HPGDNPC1RAB9ACYP19A1SMN1; SMN2
SCHEMBL8527732 0.77 CTSD (0.43) CTSDSTAT3NPC1RAB9ACYP19A1
SCHEMBL7308873 0.77 CTSD (0.43) CTSDSTAT3NPC1RAB9ACYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230407050-A1 METHOD FOR STABILIZING AN ORGANIC MATERIAL USING A STABILIZER MIXTURE BASF SE (DE) 2023-12-21 US disclosed
US-10040762-B2 Sterically hindered amines BASF SE (DE) 2018-08-07 US disclosed
US-9359485-B2 Use of non-ionic surfactants to increase oxygen scavenger activity of functionalized polyolefin films ALBIS PLASTIC GMBH (DE) 2016-06-07 US disclosed
US-9309391-B2 Process for improving the flow of properties of polymer melts BASF SE (DE) 2016-04-12 US disclosed
US-20130144011-A1 PROCESS FOR IMPROVING THE FLOW OF PROPERTIES OF POLYMER MELTS BASF SE (DE) 2013-06-06 US disclosed
US-20130053484-A1 STERICALLY HINDERED AMINES BASF SE (DE) 2013-02-28 US disclosed
US-20120187345-A1 Use of non-ionic surfactants to increase oxygen scavenger activity of functionalized polyolefin films BASF SE (DE) 2012-07-26 US disclosed
EP-2064067-A1 INK, INK CARTRIDGE, INK JET RECORDING APPARATUS, AND INK JET RECORDING METHOD Ricoh Company, Ltd. (JP) 2009-06-03 EP disclosed
EP-2054477-A1 RECORDING INK, INK/MEDIA SET, INK CARTRIDGE, INKJET RECORDING METHOD AND INKJET RECORDING APPARATUS Ricoh Company, Ltd. (JP) 2009-05-06 EP disclosed
WO-2008035797-A1 INK, INK CARTRIDGE, INK JET RECORDING APPARATUS, AND INK JET RECORDING METHOD RICOH COMPANY, LTD. (JP) 2008-03-27 WO disclosed
US-5902516-A STABILIZER FOR THERMOPLASTIC POLYOLEFIN OR ENGINEERING RESINS SUMITOMO CHEMICAL CO., LTD (JP) 1999-05-11 US disclosed
US-5891939-A POLYMER STABILIZERS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-04-06 US disclosed
US-5889095-A OXYGEN AND HEAT RESISTANCE SUMITOMO CHEMICAL COMPANY, LTD. (JP) 1999-03-30 US disclosed
US-5874494-A DETERIORATION STABILIZER FOR THERMOPLASTIC RESIN; OXIDATION RESISTANCE, DISCOLORATION INHIBITION, HEAT RESISTANCE, CROSSLINKING INHIBITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-02-23 US disclosed
US-5847187-A Organic phosphorous compound, a process for producing the same and a use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-12-08 US disclosed
US-5830936-A THERMAL STABILIZERS FOR POLYOLEFINS AND ENGINEERING PLASTICS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-11-03 US disclosed
EP-0861847-A2 Stabilizer composition and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-09-02 EP disclosed
EP-0823435-A2 Phosphites, process for producing the same and their use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-02-11 EP disclosed
WO-1995006651-A1 HYDROLYTICALLY STABLE PENTAERYTHRITOL DIPHOSPHITES DOVER CHEMICAL CORPORATION (US) 1995-03-09 WO disclosed
US-5019613-A Light stabilizers CIBA-GEIGY CORPORATION (US) 1991-05-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10040762-B2 Sterically hindered amines H1-0, F12, H1-2 CTSD 4419/4885STAT3 4053/4885HPGD 2118/4885
US-20130053484-A1 STERICALLY HINDERED AMINES H1-0, F12, H1-2 CTSD 4419/4885STAT3 4053/4885HPGD 2118/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.