SCHEMBL7651534

SCHEMBL7651534

CCCCOC(=O)C(C#N)=C(C)c1ccccc1OC

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.48
MAPK1 P28482 4/20 0.48
SMN1; SMN2 Q16637 4/20 0.48
MAPT P10636 1/20 0.48
TSHR P16473 4/20 0.47
L3MBTL1 Q9Y468 3/20 0.47
TDP1 Q9NUW8 2/20 0.47
CYP3A4 P08684 2/20 0.43
TP53 P04637 1/20 0.43
LMNA P02545 3/20 0.42
HSD17B10 Q99714 2/20 0.42
CNR1 P21554 2/20 0.41
CNR2 P34972 2/20 0.41
CYP19A1 P11511 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2C19 P33261 1/20 0.41
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
CTSD P07339 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1554328 0.87 SMN1; SMN2 (0.52) ALDH1A1SMN1; SMN2MAPTTSHRL3MBTL1
SCHEMBL1554326 0.87 SMN1; SMN2 (0.52) ALDH1A1SMN1; SMN2MAPTTSHRL3MBTL1
SCHEMBL4543403 0.82 CTSD (0.47) MAPK1SMN1; SMN2MAPTTSHRTP53
SCHEMBL76803 0.81 HPGD (0.43) ALDH1A1MAPK1SMN1; SMN2MAPTTSHR
SCHEMBL76804 0.81 HPGD (0.43) ALDH1A1MAPK1SMN1; SMN2MAPTTSHR
SCHEMBL19465674 0.78 HDAC3 (0.43) ALDH1A1MAPK1SMN1; SMN2MAPTTSHR
SCHEMBL7792874 0.77 LMNA (0.49) ALDH1A1SMN1; SMN2TP53LMNACYP19A1
SCHEMBL12755372 0.77 LMNA (0.42) ALDH1A1MAPK1SMN1; SMN2MAPTTSHR
SCHEMBL5326466 0.76 ALDH1A1 (0.51) ALDH1A1MAPK1SMN1; SMN2MAPTTSHR
SCHEMBL5326471 0.76 ALDH1A1 (0.51) ALDH1A1MAPK1SMN1; SMN2MAPTTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106255594-B Multilayer film and application thereof 巴斯夫欧洲公司 2018-12-11 CN disclosed
US-20020032256-A1 Polybutadiene composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-03-14 US disclosed