Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 5/20 | 0.49 |
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.42 |
| ▸ | PTGES | O14684 | 3/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3839542 | 0.86 | PTPN11 (0.41) | BCAT2KMT2APTPN11PTGESFFAR1 | |
| SCHEMBL26906281 | 0.81 | BCAT2 (0.72) | BCAT2NPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL1520684 | 0.81 | BCAT2 (0.72) | BCAT2NPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL4440959 | 0.77 | BCAT2 (0.50) | BCAT2NPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL4596502 | 0.77 | ADRB3 (0.53) | BCAT2LMNA | |
| SCHEMBL254315 | 0.75 | MTNR1A (0.42) | PTPN11PTGESFFAR1 | |
| SCHEMBL3840890 | 0.74 | KMT2A (0.37) | KMT2ALMNA | |
| SCHEMBL234847 | 0.74 | HRH1 (0.44) | KMT2ALMNAPTGESFFAR1 | |
| SCHEMBL5065146 | 0.73 | AOC3 (0.67) | L3MBTL1AOC3 | |
| SCHEMBL4440894 | 0.73 | PNMT (0.59) | BCAT2NPC1RAB9ASMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2638022-A1 | OXAZOLIDINONES AS MODULATORS OF MGLUR5 | Bristol-Myers Squibb Company (US) | 2013-09-18 | — | — | EP | disclosed |
| WO-2012064603-A1 | OXAZOLIDINONES AS MODULATORS OF MGLUR5 | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-05-18 | — | — | WO | disclosed |