Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.54 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.54 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.54 |
| ▸ | NISCH | Q9Y2I1 | 10/20 | 0.54 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.48 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30163845 | 0.85 | PDCD1LG2 (0.47) | ADRA2AADRA2BADRA2CNISCHMAPT | |
| SCHEMBL10651765 | 0.82 | L3MBTL1 (0.48) | ADRA2AADRA2BADRA2CNISCHAPOBEC3A | |
| SCHEMBL31658929 | 0.79 | GABRA1 (0.44) | ADRA2AADRA2BADRA2CNISCHMAPT | |
| SCHEMBL9579892 | 0.78 | NISCH (0.81) | NISCH | |
| SCHEMBL4386672 | 0.76 | NISCH (0.60) | NISCHALDH1A1TDP1 | |
| SCHEMBL11161145 | 0.76 | APOBEC3A (0.53) | ADRA2AADRA2BADRA2CAPOBEC3AAPOBEC3G | |
| SCHEMBL3360145 | 0.75 | NISCH (0.50) | ADRA2AADRA2BADRA2CNISCHMAPT | |
| SCHEMBL11757670 | 0.73 | GABRA1 (0.53) | ADRA2AADRA2BADRA2CAPOBEC3AAPOBEC3G | |
| SCHEMBL1287837 | 0.72 | ALDH1A1 (0.74) | ALDH1A1TDP1RAB9A | |
| SCHEMBL30535903 | 0.72 | ALDH1A1 (0.74) | ALDH1A1TDP1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7629463-B2 | Ortho-heterocyclic substituted aryl amides for controlling invertebrate pests | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-12-08 | — | — | US | disclosed |
| US-20080132524-A1 | Ortho-heterocyclic substituted aryl amides for controlling invertebrate pests | CLARK DAVID ALAN | 2008-06-05 | — | — | US | disclosed |
| US-7375232-B2 | Ortho-heterocyclic substituted aryl amides for controlling invertebrate pests | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-05-20 | — | — | US | disclosed |
| EP-1417204-B1 | ORTHO-HETEROCYCLIC SUBSTITUTED ARYL AMIDES FOR CONTROLLING INVERTEBRATE PESTS | DU PONT (US) | 2006-01-18 | — | — | EP | disclosed |
| US-20040242645-A1 | Ortho-heterocyclic substituted aryl amides for controlling invertebrate pests | E. I. DU PONT DE NEMOURS AND COMPANY | 2004-12-02 | — | — | US | disclosed |
| EP-1417204-A1 | ORTHO-HETEROCYCLIC SUBSTITUTED ARYL AMIDES FOR CONTROLLING INVERTEBRATE PESTS | E. I. du Pont de Nemours and Company (US) | 2004-05-12 | — | — | EP | disclosed |
| WO-2003016304-A1 | ORTHO-HETEROCYCLIC SUBSTITUTED ARYL AMIDES FOR CONTROLLING INVERTEBRATE PESTS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2003-02-27 | — | — | WO | disclosed |
| EP-0331507-B1 | POLYVINYL CHLORIDE PLASTISOL COMPOSITION | ASAHI DENKA KOGYO KABUSHIKI KAISHA (JP) | 1993-05-19 | — | — | EP | disclosed |
| US-4977201-A | Blended with modified epoxy resin, blocked isocyanate, latent curing for resin as tackifier, automobile undercoatings | ASAHI DENKA KOGYO K.K. (JP) | 1990-12-11 | — | — | US | disclosed |
| EP-0331507-A1 | Polyvinyl chloride plastisol composition | ASAHI DENKA KOGYO KABUSHIKI KAISHA (JP) | 1989-09-06 | — | — | EP | disclosed |
| EP-0046446-A1 | Polyazaheterocyclic compounds, process for their preparation and pharmaceutical compositions containing them | CIBA-GEIGY AG (CH) | 1982-02-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080132524-A1 | Ortho-heterocyclic substituted aryl amides for controlling invertebrate pests | AOC2, DDT, CBR3 | ADRA2A 1486/4885ADRA2B 1694/4885ADRA2C 757/4885 |
| US-20040242645-A1 | Ortho-heterocyclic substituted aryl amides for controlling invertebrate pests | AOC2, OLA1, AOC3 | ADRA2A 1304/4885ADRA2B 1114/4885ADRA2C 628/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.