Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 1/20 | 0.42 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | ADCY10 | Q96PN6 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9684086 | 0.85 | SLC6A4 (0.46) | — | |
| SCHEMBL4544029 | 0.80 | AGTR1 (0.54) | — | |
| SCHEMBL8439141 | 0.69 | AGTR1 (0.53) | — | |
| SCHEMBL9683640 | 0.69 | GP6 (0.46) | — | |
| SCHEMBL31362217 | 0.69 | PTGDR2 (0.56) | NPBWR1ALDH1A1LMNAPTGDR2 | |
| SCHEMBL417 | 0.67 | SLC6A4 (0.46) | — | |
| SCHEMBL156281 | 0.65 | ALDH1A1 (0.66) | ALDH1A1LMNAGAAMAPTHIF1A | |
| SCHEMBL1786603 | 0.64 | TSHR (0.52) | ALDH1A1LMNAGAAMAPTKMT2A | |
| Hydrochloric Acid SCHEMBL11601329 | 0.63 | ALDH1A1 (0.55) | ALDH1A1LMNAGAAMAPTHIF1A | |
| SCHEMBL12032474 | 0.63 | ALDH1A1 (0.58) | NPBWR1ALDH1A1LMNAGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009084028-A2 | IMPROVED PROCESS FOR MANUFACTURING ANHYDROUS (E)-3-[2-BUTYL-1- {(4-CARBOXYPHENYL) METHYL}-1H-IMIDAZOLE-5-YL]-(THIOPHEN-2- YLMETHYL)PROP-2-ENOIC ACID METHANE SULFONATE | NEULAND LABORATORIES LTD (IN) | 2009-07-09 | — | — | WO | disclosed |