SCHEMBL4547555

SCHEMBL4547555

COc1cccc(Nc2nc(Nc3cccc(CO)c3)nc(Nc3ccccc3C)n2)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNH3 Q9ULD8 2/20 0.50
HTT P42858 2/20 0.47
KDM4E B2RXH2 1/20 0.47
TAAR1 Q96RJ0 1/20 0.47
GBA1 P04062 1/20 0.47
VSIR Q9H7M9 1/20 0.47
POLB P06746 2/20 0.46
NPC1 O15118 1/20 0.46
RAB9A P51151 1/20 0.46
MAPT P10636 2/20 0.45
TP53 P04637 2/20 0.45
TSHR P16473 4/20 0.45
USP2 O75604 4/20 0.45
CYP1A2 P05177 4/20 0.45
CYP3A4 P08684 4/20 0.45
CYP2C9 P11712 4/20 0.45
CLK4 Q9HAZ1 4/20 0.45
MEN1 O00255 3/20 0.45
KMT2A Q03164 3/20 0.45
ALDH1A1 P00352 3/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4544824 0.89 KCNH3 (0.60) KCNH3HTTPOLBNPC1RAB9A
SCHEMBL4547448 0.88 SIRT1 (0.49) KCNH3HTTKDM4ETAAR1GBA1
SCHEMBL4544869 0.87 KCNH3 (0.58) KCNH3HTTKDM4ETAAR1POLB
SCHEMBL4547556 0.86 KCNH3 (0.54) KCNH3HTTKDM4ETAAR1GBA1
SCHEMBL4547557 0.85 KCNH3 (0.53) KCNH3HTTKDM4ETAAR1GBA1
SCHEMBL4547558 0.84 KCNH3 (0.55) KCNH3HTTKDM4ETAAR1GBA1
SCHEMBL4547449 0.82 EGFR (0.55) KCNH3HTTKDM4ETAAR1GBA1
SCHEMBL12642726 0.81 TSHR (0.46) KCNH3HTTPOLBNPC1RAB9A
SCHEMBL14116665 0.80 KCNH3 (0.50) KCNH3HTTVSIRPOLBNPC1
SCHEMBL14184957 0.79 APP (0.50) KCNH3NPC1RAB9AMAPTTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8395727-B2 VA mode liquid crystal display device FUJIFILM CORPORATION (JP) 2013-03-12 US disclosed
US-8350999-B2 Liquid-crystal display device having particular retardations and internal hazes FUJIFILM CORPORATION (JP) 2013-01-08 US disclosed
US-20120236234-A1 VA-MODE LIQUID-CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2012-09-20 US disclosed
US-20120236235-A1 LIQUID-CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2012-09-20 US disclosed
US-20120236233-A1 VA-MODE LIQUID-CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2012-09-20 US disclosed
US-8203675-B2 Liquid-crystal display device having retardation films with different optical anisotropy FUJIFILM CORPORATION (JP) 2012-06-19 US disclosed
US-20120120348-A1 VA-MODE LIQUID-CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2012-05-17 US disclosed
US-8178601-B2 Polymer film, polarizing plate protective film, polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2012-05-15 US disclosed
US-20110311738-A1 Process of producing cellulose acylate film, cellulose acylate film, polarizing plate liquid crystal display device and optical compensation film FUJIFILM CORPORATION (JP) 2011-12-22 US disclosed
US-7990502-B2 Liquid-crystal display device FUJIFILM CORPORATION (JP) 2011-08-02 US disclosed
US-20090066887-A1 Polymer Film, Polarizing Plate Protective Film, Polarizing Plate and Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2009-03-12 US disclosed
US-20080226888-A1 Cellulose Acylate Film, Polarizing Plate and Liquid Crystal Display Device Using the Same FUJIFILM CORPORATION (JP) 2008-09-18 US disclosed
US-20080213511-A1 Optical compensation film, process for producing optical compensation film, polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2008-09-04 US disclosed
US-20080204644-A1 Liquid crystal display device FUJIFILM CORPORATION (JP) 2008-08-28 US disclosed
US-20080198303-A1 Polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2008-08-21 US disclosed
US-20080192192-A1 Optical film and polarizing plate FUJIFILM CORPORATION (JP) 2008-08-14 US disclosed
US-20080174724-A1 Liquid crystal display device, optical film and polarizing plate FUJIFILM CORPORATION (JP) 2008-07-24 US disclosed
US-20080158488-A1 Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2008-07-03 US disclosed
US-20080143928-A1 Polarizing Plate and Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2008-06-19 US disclosed
US-20080137014-A1 Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2008-06-12 US disclosed