Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | RARB | P10826 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | STS | P08842 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4544991 | 0.76 | ALDH1A1 (0.43) | ALDH1A1NPC1MAPTRAB9ATSHR | |
| SCHEMBL4544967 | 0.75 | ALDH1A1 (0.40) | ALDH1A1NPC1MAPTRAB9ATSHR | |
| SCHEMBL4544956 | 0.70 | TSHR (0.51) | TSHR | |
| SCHEMBL4544964 | 0.69 | TSHR (0.50) | TSHR | |
| SCHEMBL13913175 | 0.67 | TP53 (0.55) | NPC1MAPTRAB9ATSHRTP53 | |
| SCHEMBL4544983 | 0.66 | TSHR (0.46) | ALDH1A1TSHR | |
| SCHEMBL4544980 | 0.66 | TSHR (0.46) | ALDH1A1TSHR | |
| SCHEMBL2184869 | 0.66 | ALDH1A1 (0.66) | ALDH1A1NPC1MAPTRAB9ATSHR | |
| SCHEMBL4544977 | 0.66 | TSHR (0.46) | ALDH1A1TSHR | |
| SCHEMBL4544971 | 0.66 | TSHR (0.46) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8298736-B2 | Electrophotographic toner | KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) | 2012-10-30 | — | — | US | disclosed |
| US-8178267-B2 | Electrophotographic toner | KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) | 2012-05-15 | — | — | US | disclosed |
| US-20090291377-A1 | ELECTROPHOTOGRAPHIC TONER | KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) | 2009-11-26 | — | — | US | disclosed |
| US-20090291381-A1 | ELECTROPHOTOGRAPHIC TONER | KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) | 2009-11-26 | — | — | US | disclosed |
| US-20090233207-A1 | PYRAZOLOTRIAZOLE COMPOUND AND ELECTROPHOTOGRAPHIC TONER | KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) | 2009-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090233207-A1 | PYRAZOLOTRIAZOLE COMPOUND AND ELECTROPHOTOGRAPHIC TONER | HAX1, XDH, GLRX3 | PLA2G2D 3924/4885ALDH1A1 3741/4885NPC1 4186/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.