Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ALPI | P09923 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4544949 | 0.89 | TSHR (0.48) | LMNANPC1CYP3A4SMN1; SMN2L3MBTL1 | |
| SCHEMBL4544986 | 0.88 | TSHR (0.49) | LMNANPC1CYP3A4SMN1; SMN2TSHR | |
| SCHEMBL4544968 | 0.82 | LMNA (0.52) | LMNANPC1CYP3A4CYP1A2CYP2D6 | |
| SCHEMBL4544967 | 0.81 | ALDH1A1 (0.40) | LMNANPC1TSHRTP53ALDH1A1 | |
| Isonicotinic Acid Pentyl Ester SCHEMBL1645891 | 0.75 | LMNA (0.66) | LMNANPC1CYP3A4CYP1A2CYP2D6 | |
| Isonicotinic Acid Hexyl Ester SCHEMBL4951158 | 0.74 | LMNA (0.68) | LMNANPC1CYP3A4CYP1A2CYP2D6 | |
| N-Decyl Isonicotinate SCHEMBL4957558 | 0.74 | LMNA (0.68) | LMNANPC1CYP3A4CYP1A2CYP2D6 | |
| SCHEMBL4544970 | 0.74 | TSHR (0.54) | LMNANAAATSHRALDH1A1 | |
| SCHEMBL4544960 | 0.74 | TSHR (0.54) | LMNANAAATSHRALDH1A1 | |
| SCHEMBL10780701 | 0.74 | LMNA (0.68) | LMNANPC1CYP3A4CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8298736-B2 | Electrophotographic toner | KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) | 2012-10-30 | — | — | US | disclosed |
| US-8178267-B2 | Electrophotographic toner | KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) | 2012-05-15 | — | — | US | disclosed |
| US-20090291377-A1 | ELECTROPHOTOGRAPHIC TONER | KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) | 2009-11-26 | — | — | US | disclosed |
| US-20090291381-A1 | ELECTROPHOTOGRAPHIC TONER | KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) | 2009-11-26 | — | — | US | disclosed |
| US-20090233207-A1 | PYRAZOLOTRIAZOLE COMPOUND AND ELECTROPHOTOGRAPHIC TONER | KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) | 2009-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090233207-A1 | PYRAZOLOTRIAZOLE COMPOUND AND ELECTROPHOTOGRAPHIC TONER | HAX1, XDH, GLRX3 | LMNA 4159/4885NPC1 4186/4885CYP3A4 78/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.