SCHEMBL4545256

SCHEMBL4545256

CCOS(=O)(=O)CC1CC2C=CC1C2

nearest known ligand 0.47

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 11/20 0.41
ALDH1A1 P00352 5/20 0.41
PKM P14618 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
HTT P42858 1/20 0.32
TSHR P16473 1/20 0.31
POLB P06746 1/20 0.31
ALOX15 P16050 1/20 0.31
LMNA P02545 1/20 0.31
MAPT P10636 1/20 0.31
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14344176 0.80 KDM4E (0.47) KDM4EALDH1A1PKMTDP1MEN1
SCHEMBL109060 0.78
SCHEMBL4391217 0.75 KDM4E (0.41) KDM4EALDH1A1PKMTDP1MEN1
Ethylene SCHEMBL9419360 0.74 KDM4E (0.52) KDM4EALDH1A1TDP1MEN1KMT2A
SCHEMBL13259889 0.73 KDM4E (0.43) KDM4EALDH1A1PKMTDP1MEN1
SCHEMBL4385827 0.72 KDM4E (0.43) KDM4EALDH1A1PKMTDP1MEN1
SCHEMBL4545253 0.72 KDM4E (0.37) KDM4EALDH1A1LMNA
SCHEMBL13409258 0.72 KDM4E (0.43) KDM4EALDH1A1PKMTDP1MEN1
SCHEMBL4545262 0.71
SCHEMBL4391305 0.70 KDM4E (0.34) KDM4EALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8168349-B2 Fuel cell-purpose electrolyte material and production method therefor TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) 2012-05-01 US disclosed
US-20090136819-A1 Fuel Cell-Purpose Electrolyte Material and Production Method Therefor TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) 2009-05-28 US disclosed
WO-2007096747-A1 FUEL CELL-PURPOSE ELECTROLYTE MATERIAL AND PRODUCTION METHOD THEREFOR TOYOTA JIDOSHA KABUSHIKI KAISHA (DE) 2007-08-30 WO disclosed