Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDHD2 | O94830 | 1/20 | 0.42 |
| ▸ | SLC6A9 | P48067 | 8/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.40 |
| ▸ | SLC6A5 | Q9Y345 | 6/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.40 |
| ▸ | GCGR | P47871 | 3/20 | 0.40 |
| ▸ | GIPR | P48546 | 3/20 | 0.40 |
| ▸ | DAGLB | Q8NCG7 | 1/20 | 0.39 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | CCR5 | P51681 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15104629 | 0.84 | DAGLB (0.44) | DDHD2SLC6A9KCNH2SLC6A5CYP2D6 | |
| SCHEMBL4545282 | 0.84 | SLC6A9 (0.39) | SLC6A9KCNH2SLC6A5ABL1CYP3A4 | |
| SCHEMBL4545279 | 0.83 | PDE4D (0.40) | SLC6A9KCNH2SLC6A5 | |
| SCHEMBL4545281 | 0.82 | ABL1 (0.41) | FFAR4ABL1NTRK1FFAR1 | |
| SCHEMBL2686248 | 0.80 | SLC6A9 (0.42) | SLC6A9KCNH2SLC6A5CYP2D6CYP3A4 | |
| SCHEMBL407459 | 0.78 | SLC6A9 (0.54) | SLC6A9KCNH2SLC6A5CYP2D6CYP3A4 | |
| SCHEMBL15104660 | 0.77 | SLC6A9 (0.46) | SLC6A9KCNH2SLC6A5CYP2D6DAGLB | |
| SCHEMBL10064761 | 0.77 | SLC6A9 (0.56) | SLC6A9KCNH2SLC6A5CYP2D6CYP3A4 | |
| SCHEMBL15116033 | 0.77 | PIK3CA (0.38) | SLC6A9KCNH2SLC6A5CYP2D6CYP3A4 | |
| SCHEMBL374972 | 0.76 | SLC6A9 (0.40) | SLC6A9KCNH2SLC6A5CYP2D6ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120116095-A1 | GLYCINE TRANSPORTER INHIBITORS | TAISHO PHARMACEUTICAL C0., LTD. (JP) | 2012-05-10 | — | — | US | disclosed |
| US-20120116095-A1 | GLYCINE TRANSPORTER INHIBITORS | TAISHO PHARMACEUTICAL C0., LTD. (JP) | 2012-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120116095-A1 | GLYCINE TRANSPORTER INHIBITORS | SLC6A5, SLC1A2, SLC18A2 | DDHD2 2316/4885SLC6A9 5/4885KCNH2 1410/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.