Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 7/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.42 |
| ▸ | SLC6A5 | Q9Y345 | 4/20 | 0.41 |
| ▸ | AXL | P30530 | 1/20 | 0.40 |
| ▸ | MERTK | Q12866 | 1/20 | 0.40 |
| ▸ | AGER | Q15109 | 3/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15104641 | 0.90 | SLC6A9 (0.40) | SLC6A9KCNH2SLC6A5AXLMERTK | |
| SCHEMBL999445 | 0.82 | SLC6A9 (0.60) | SLC6A9KCNH2SLC6A5AGERMTNR1A | |
| SCHEMBL15104548 | 0.82 | SLC6A9 (0.38) | SLC6A9KCNH2SLC6A5AGERMTNR1A | |
| SCHEMBL4545282 | 0.81 | SLC6A9 (0.39) | SLC6A9KCNH2SLC6A5AXLMERTK | |
| SCHEMBL1049622 | 0.81 | SLC6A9 (0.61) | SLC6A9KCNH2SLC6A5CYP3A4CYP2D6 | |
| SCHEMBL4545285 | 0.80 | DDHD2 (0.42) | SLC6A9KCNH2SLC6A5CYP3A4CYP2D6 | |
| SCHEMBL2686649 | 0.80 | AGER (0.41) | SLC6A9KCNH2SLC6A5AGERMTNR1A | |
| SCHEMBL15104642 | 0.80 | SLC6A9 (0.60) | SLC6A9KCNH2SLC6A5CYP3A4CYP2D6 | |
| SCHEMBL4545279 | 0.79 | PDE4D (0.40) | SLC6A9KCNH2SLC6A5AGERMTNR1A | |
| SCHEMBL1051680 | 0.79 | HDAC8 (0.40) | SLC6A9KCNH2AXLMERTKMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120116095-A1 | GLYCINE TRANSPORTER INHIBITORS | TAISHO PHARMACEUTICAL C0., LTD. (JP) | 2012-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120116095-A1 | GLYCINE TRANSPORTER INHIBITORS | SLC6A5, SLC1A2, SLC18A2 | SLC6A9 5/4885KCNH2 1410/4885SLC6A5 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.