SCHEMBL4546795

SCHEMBL4546795

COCCOCCOCCOCCOCCOCCOP(=O)(O)OC

nearest known ligand 0.39

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PLA2G2A P14555 2/20 0.39
CYP3A4 P08684 1/20 0.39
TSHR P16473 1/20 0.39
CA2 P00918 2/20 0.34
BTN3A1 O00481 1/20 0.34
ALDH1A1 P00352 1/20 0.31
LPAR3 Q9UBY5 3/20 0.30
LPAR1 Q92633 2/20 0.30
LPAR2 Q9HBW0 2/20 0.30
MVD P53602 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20261774 1.00 PLA2G2A (0.39) PLA2G2ACYP3A4TSHRCA2BTN3A1
SCHEMBL12638785 1.00 PLA2G2A (0.39) PLA2G2ACYP3A4TSHRCA2BTN3A1
SCHEMBL20261782 1.00 PLA2G2A (0.39) PLA2G2ACYP3A4TSHRCA2BTN3A1
SCHEMBL14802705 0.95 CYP3A4 (0.41) PLA2G2ACYP3A4TSHRBTN3A1ALDH1A1
SCHEMBL19699812 0.95 CYP3A4 (0.41) PLA2G2ACYP3A4TSHRBTN3A1ALDH1A1
SCHEMBL6352756 0.93 BTN3A1 (0.38) PLA2G2ATSHRCA2BTN3A1ALDH1A1
SCHEMBL20213370 0.91 TSHR (0.41) PLA2G2ACYP3A4TSHRCA2BTN3A1
SCHEMBL20213334 0.91 TSHR (0.41) PLA2G2ACYP3A4TSHRCA2BTN3A1
SCHEMBL20278340 0.87 TSHR (0.41) PLA2G2ACYP3A4TSHRBTN3A1ALDH1A1
SCHEMBL19912248 0.87 CYP3A4 (0.45) PLA2G2ACYP3A4TSHRBTN3A1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240026421-A1 METHODS FOR CAPTURING LONG POLYNUCLEOTIDES FOR SEQUENCING SPECIFIC GENOMIC REGIONS GENERATION BIOTECH, LLC (US) 2024-01-25 US disclosed
US-11821023-B2 Method for capturing long polynucleotides for sequencing specific gnomic regions GENERATION BIOTECH, LLC (US) 2023-11-21 US disclosed
US-20200390904-A1 ANTI-NUCLEOLIN AGENT-CONJUGATED NANOPARTICLES AS RADIO-SENSITIZERS AND MRI AND/OR X-RAY CONTRAST AGENTS UNIV LOUISVILLE RES FOUND INC (US) 2020-12-17 US disclosed
WO-2019153677-A1 NEW METHOD FOR VISUAL QUANTITATIVE DETECTION OF DUAL HEAVY METAL IONS 中国农业大学 2019-08-15 WO disclosed
US-20180042849-A1 COCHLEATES AND METHODS OF USING THE SAME TO ENHANCE TISSUE PENETRATION OF PHARMACOLOGICALLY ACTIVE AGENT AQUARIUS BIOTECHNOLOGIES, INC. 2018-02-15 US disclosed
US-9551028-B2 Nucleic acid sequence analysis PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2017-01-24 US disclosed
US-9499859-B2 Method for detecting a circularized DNA, and use of said method for detecting mutations Bockelmann, Ulrich (FR) 2016-11-22 US disclosed
US-20150167071-A1 NUCLEIC ACID SEQUENCE ANALYSIS PACIFIC BIOSCIENCES CALIFORNIA (US) 2015-06-18 US disclosed
US-8921046-B2 Nucleic acid sequence analysis PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2014-12-30 US disclosed
US-8853134-B2 Microarrays of binary nucleic acid probes for detecting nucleic acid analytes THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2014-10-07 US disclosed
US-20130130323-A1 PREVENTION AND ALLEVIATION OF STERIC HINDRANCE DURING SINGLE MOLECULE SYNTHESIS PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2013-05-23 US disclosed
US-8313903-B2 Binary DNA probe for fluorescent analysis of nucleic acids THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2012-11-20 US disclosed
US-20120264630-A1 METHOD FOR DETECTING A CIRCULARIZED DNA, AND USE OF SAID METHOD FOR DETECTING MUTATIONS BOCKELMANN, ULRICH (FR) 2012-10-18 US disclosed
US-8198023-B2 Prevention and alleviation of steric hindrance during single molecule nucleic acid synthesis by a polymerase PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2012-06-12 US disclosed
US-20120115736-A1 NUCLEIC ACID SEQUENCE ANALYSIS PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2012-05-10 US disclosed
US-20120040867-A1 Microarrays of Binary Nucleic Acid Probes for Detecting Nucleic Acid Analytes THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2012-02-16 US disclosed
US-7939654-B2 Platelet derived growth factor (PDGF) nucleic acid ligand complexes GILEAD SCIENCES, INC. (US) 2011-05-10 US disclosed
US-20100075328-A1 IMMOBILIZED NUCLEIC ACID COMPLEXES FOR SEQUENCE ANALYSIS PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2010-03-25 US disclosed
US-20100035269-A1 PREVENTION AND ALLEVIATION OF STERIC HINDRANCE DURING SINGLE MOLECULE SYNTHESIS PACIFIC BIOSCIENCES OF CALIFORNIA, INC. 2010-02-11 US disclosed
US-20090176318-A1 BINARY DNA PROBE FOR FLUORESCENT ANALYSIS OF NUCLEIC ACIDS COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK 2009-07-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200390904-A1 ANTI-NUCLEOLIN AGENT-CONJUGATED NANOPARTICLES AS RADIO-SENSITIZERS AND MRI AND/OR X-RAY CONTRAST AGENTS NCL, HNRNPA1, HNRNPR PLA2G2A 3440/4885CYP3A4 4761/4885TSHR 2194/4885
US-20180042849-A1 COCHLEATES AND METHODS OF USING THE SAME TO ENHANCE TISSUE PENETRATION OF PHARMACOLOGICALLY ACTIVE AGENT SLC10A1, SLC10A2, PCYT1A PLA2G2A 910/4885CYP3A4 3727/4885TSHR 3476/4885
US-20090176318-A1 BINARY DNA PROBE FOR FLUORESCENT ANALYSIS OF NUCLEIC ACIDS SSBP1, MDH1, SNRPE PLA2G2A 4823/4885CYP3A4 833/4885TSHR 4060/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.