Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22817324 | 0.86 | CYP1A2 (0.33) | HDAC1HDAC6 | |
| SCHEMBL15241715 | 0.78 | RAPGEF4 (0.35) | — | |
| SCHEMBL28880200 | 0.78 | HMGB1 (0.40) | HDAC1HDAC6ALDH1A1 | |
| SCHEMBL13932538 | 0.78 | HDAC1 (0.38) | HDAC1HDAC6 | |
| SCHEMBL391029 | 0.78 | CES2 (0.36) | TRPA1ALDH1A1TSHR | |
| SCHEMBL18553018 | 0.78 | PTGS1 (0.40) | HDAC1HDAC6 | |
| SCHEMBL24357406 | 0.77 | — | — | |
| SCHEMBL30626589 | 0.77 | — | — | |
| SCHEMBL24357673 | 0.76 | KDM1A (0.37) | TRPA1ALDH1A1TSHR | |
| SCHEMBL6886890 | 0.76 | HDAC1 (0.37) | HDAC1HDAC6TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250243205-A1 | sGC STIMULATORS | TISENTO THERAPEUTICS INC (US) | 2025-07-31 | — | — | US | disclosed |
| US-20250059197-A1 | sGC STIMULATORS | TISENTO THERAPEUTICS INC (US) | 2025-02-20 | — | — | US | disclosed |
| US-11897887-B2 | sGC stimulators | TISENTO THERAPEUTICS INC. (US) | 2024-02-13 | — | — | US | disclosed |
| CN-111712247-B | sGC stimulators | 塞科里昂医疗股份有限公司 | 2024-02-09 | — | — | CN | disclosed |
| EP-3342766-B1 | SMALL MOLECULE COMPOUND FOR ENHANCING PLANT STRESS RESISTANCE | CAS CENTER FOR EXCELLENCE IN MOLECULAR PLANT SCIENCES (CN) | 2020-12-09 | — | — | EP | disclosed |
| US-20200377508-A1 | sGC STIMULATORS | TISENTO THERAPEUTICS INC. | 2020-12-03 | — | — | US | disclosed |
| US-10842151-B2 | Small molecule compound for enhancing plant stress resistance | CAS CENTER FOR EXCELLENCE IN MOLECULAR PLANT SCIENCES (CN) | 2020-11-24 | — | — | US | disclosed |
| EP-3727388-A1 | SGC STIMULATORS | Cyclerion Therapeutics, Inc. (US) | 2020-10-28 | — | — | EP | disclosed |
| CN-111712247-A | sGC stimulators | 塞科里昂医疗股份有限公司 | 2020-09-25 | — | — | CN | disclosed |
| US-20180360039-A1 | Small Molecule Compound for Enhancing Plant Stress Resistance | CAS CENTER FOR EXCELLENCE IN MOLECULAR PLANT SCIENCES (CN) | 2018-12-20 | — | — | US | disclosed |
| EP-3342766-A1 | SMALL MOLECULE COMPOUND FOR ENHANCING PLANT STRESS RESISTANCE | Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences (CN) | 2018-07-04 | — | — | EP | disclosed |
| US-8173704-B2 | Difluorophenol derivatives and their use | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-05-08 | — | — | US | disclosed |
| US-20090291993-A1 | Difluorophenol Derivatives and Their Use | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2009-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250059197-A1 | sGC STIMULATORS | GMPS, GUCY1A2, PDE2A | HDAC1 3330/4885HDAC6 3716/4885TRPA1 2486/4885 |
| US-20090291993-A1 | Difluorophenol Derivatives and Their Use | TPMT, FABP3, DPP4 | HDAC1 1744/4885HDAC6 1012/4885TRPA1 3762/4885 |
| US-11897887-B2 | sGC stimulators | GMPS, GUCY1A2, PDE2A | HDAC1 3404/4885HDAC6 3836/4885TRPA1 2400/4885 |
| US-10842151-B2 | Small molecule compound for enhancing plant stress resistance | CYP4F11, RICTOR, MYB | HDAC1 1165/4885HDAC6 2131/4885TRPA1 256/4885 |
| US-20200377508-A1 | sGC STIMULATORS | GMPS, GUCY1A2, PDE2A | HDAC1 3404/4885HDAC6 3836/4885TRPA1 2400/4885 |
| US-20180360039-A1 | Small Molecule Compound for Enhancing Plant Stress Resistance | CYP4F11, RICTOR, MYB | HDAC1 1165/4885HDAC6 2131/4885TRPA1 256/4885 |
| US-20250243205-A1 | sGC STIMULATORS | GMPS, GUCY1A2, PDE2A | HDAC1 3330/4885HDAC6 3716/4885TRPA1 2486/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.