SCHEMBL391029

SCHEMBL391029

Fc1cc(CBr)cc(F)c1F

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.36
CES1 P23141 1/20 0.36
TRPA1 O75762 2/20 0.35
ALDH1A1 P00352 1/20 0.35
TSHR P16473 1/20 0.35
MAOB P27338 1/20 0.32
RIPK1 Q13546 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31338758 0.85 CYP1A2 (0.31)
SCHEMBL15241715 0.83 RAPGEF4 (0.35)
SCHEMBL24357673 0.80 KDM1A (0.37) TRPA1ALDH1A1TSHR
SCHEMBL29738508 0.79 KIF11 (0.33)
SCHEMBL24852353 0.79 KIF11 (0.33)
SCHEMBL27161330 0.79 HTR2A (0.38) ALDH1A1TSHR
SCHEMBL6167933 0.78 MEP1B (0.46) TRPA1ALDH1A1TSHR
SCHEMBL25219828 0.78 TRPA1 (0.32) TRPA1ALDH1A1TSHR
SCHEMBL4547659 0.78 HDAC1 (0.35) TRPA1ALDH1A1TSHR
SCHEMBL7762516 0.78 TDP1 (0.40) CES2CES1MAOBRIPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 391 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119465288-A Anion exchange membrane, preparation method and application thereof, and electrolysis device 氢和元泰(常州)新材料科技有限公司 2025-02-18 CN claimed
CN-118063504-A Fluoro phenyl phosphate compound, perovskite thin film, perovskite solar cell, preparation method, electric equipment and application 天合光能股份有限公司 2024-05-24 CN claimed
CN-122055361-A Fascin inhibitors 北京双鹤润创科技有限公司 2026-05-15 CN disclosed
US-20260125365-A1 TRIAZINE DERIVATIVES HAVING VIRUS REPLICATION INHIBITORY ACTIVITY AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME SHIONOGI & CO., LTD. (JP) 2026-05-07 US disclosed
EP-4720054-A1 FASCIN INHIBITORS Beijing Double-Crane Runchuang Technology Co., Ltd. (CN) 2026-04-08 EP disclosed
US-20260070945-A1 MACROCYCLIC IMMUNOMODULATORS BRISTOL-MYERS SQUIBB COMPANY 2026-03-12 US disclosed
US-12559474-B2 Triazine derivatives having virus replication inhibitory activity and pharmaceutical composition comprising the same SHIONOGI & CO., LTD. (JP) 2026-02-24 US disclosed
US-20260034123-A1 CDK2 INHIBITORS AND METHODS OF USING THE SAME CEDILLA THERAPEUTICS INC (US) 2026-02-05 US disclosed
US-20260022142-A1 MACROCYCLIC IMMUNOMODULATORS BRISTOL MYERS SQUIBB CO (US) 2026-01-22 US disclosed
EP-4655069-A1 PYRIDAZINES AS SARM1 INHIBITORS Disarm Therapeutics, Inc. (US) 2025-12-03 EP disclosed
US-12410183-B2 Sars-cov2 main protease inhibitors GILEAD SCIENCES, INC. (US) 2025-09-09 US disclosed
EP-1568754-A1 NEMATIC LIQUID CRYSTAL COMPOSITION CONTAINING INDAN COMPOUND DAINIPPON INK AND CHEMICALS, INC. (JP) 2005-08-31 EP disclosed
EP-1515968-A2 QUINUCLIDINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME Almirall Prodesfarma AG (CH) 2005-03-23 EP disclosed
WO-2004085403-A1 TETRAHYDROISOQUINOLYL ACETAMIDE DERIVATIVES FOR USE AS OREXIN RECEPTOR ANTAGONISTS ACTELION PHARMACEUTICALS LTD (CH) 2004-10-07 WO disclosed
WO-2004000840-A2 QUINUCLIDINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME ALMIRALL PRODESFARMA AG (CH) 2003-12-31 WO disclosed
CN-1443164-A Pyrrolidine derivatives as metalloprotease inhibitors HOFFMANN LA ROCHE (CH) 2003-09-17 CN disclosed
CN-1391562-A Quinazoline derivatives as medicaments ASTRAZENECA AB (SE) 2003-01-15 CN disclosed
EP-1218354-A1 QUINAZOLINE DERIVATIVES AND THEIR USE AS PHARMACEUTICALS AstraZeneca AB (SE) 2002-07-03 EP disclosed
CN-1073112-C Optionally substituted 8-cyano-1-cyclopropyl-7- (2, 8-diazabicyclo [4.3.0] non-8-yl) -6-fluoro-1, 4-dihydro-4-oxo-3-quinolinecarboxylic acid and derivatives thereof BAYER AG (DE) 2001-10-17 CN disclosed
WO-2001021596-A1 QUINAZOLINE DERIVATIVES AND THEIR USE AS PHARMACEUTICALS ASTRAZENECA AB (SE) 2001-03-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260034123-A1 CDK2 INHIBITORS AND METHODS OF USING THE SAME CDK2, CDK1, CDK20 CES2 4190/4885CES1 2645/4885TRPA1 4747/4885
US-20260022142-A1 MACROCYCLIC IMMUNOMODULATORS CD274, PDCD1LG2, PDCD1 CES2 2983/4885CES1 626/4885TRPA1 4406/4885
US-20260070945-A1 MACROCYCLIC IMMUNOMODULATORS CD274, PDCD1, PDCD1LG2 CES2 2350/4885CES1 522/4885TRPA1 3826/4885
US-12410183-B2 Sars-cov2 main protease inhibitors ACE2, TMPRSS2, ACE CES2 277/4885CES1 145/4885TRPA1 3385/4885
US-12559474-B2 Triazine derivatives having virus replication inhibitory activity and pharmaceutical composition comprising the same NSUN2, ZC3HAV1, IFNAR1 CES2 522/4885CES1 455/4885TRPA1 4823/4885
US-20260125365-A1 TRIAZINE DERIVATIVES HAVING VIRUS REPLICATION INHIBITORY ACTIVITY AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME ACE2, ACE, SARS1 CES2 449/4885CES1 160/4885TRPA1 4463/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.