Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | PREP | P48147 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12459282 | 0.85 | LMNA (0.56) | LMNABACE1GAAALDH1A1TDP1 | |
| SCHEMBL4547745 | 0.79 | MEN1 (0.49) | PREPALDH1A1TDP1SMN1; SMN2MEN1 | |
| SCHEMBL14879090 | 0.76 | LMNA (0.47) | LMNABACE1GAAALDH1A1TDP1 | |
| SCHEMBL11919002 | 0.75 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL12332368 | 0.75 | LMNA (0.54) | LMNAGAAALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL6197701 | 0.75 | LMNA (0.54) | LMNAGAAALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL7751129 | 0.75 | LMNA (0.59) | LMNAGAAALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL319174 | 0.73 | LMNA (0.52) | LMNAGAAALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL38657619 | 0.72 | LMNA (0.50) | LMNAGAAALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL29466146 | 0.72 | LMNA (0.50) | LMNAGAAALDH1A1TDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1601999-B1 | Holographic sensor and its use | SMART HOLOGRAMS LTD (GB) | 2013-04-24 | — | — | EP | disclosed |
| US-8241574-B2 | Ophthalmic device comprising a holographic sensor | SMART HOLOGRAMS LIMITED (GB) | 2012-08-14 | — | — | US | disclosed |
| US-8241574-B2 | Ophthalmic device comprising a holographic sensor | SMART HOLOGRAMS LIMITED (GB) | 2012-08-14 | — | — | US | disclosed |
| US-20120107944-A1 | Holographic Sensor | LOWE CHRISTOPHER ROBIN (GB) | 2012-05-03 | — | — | US | disclosed |
| US-20120107944-A1 | Holographic Sensor | LOWE CHRISTOPHER ROBIN (GB) | 2012-05-03 | — | — | US | disclosed |
| US-20110286064-A1 | OPHTHALMIC DEVICE COMPRISING A HOLOGRAPHIC SENSOR | BURLES BARRY (GB) | 2011-11-24 | — | — | US | disclosed |
| US-20110286064-A1 | OPHTHALMIC DEVICE COMPRISING A HOLOGRAPHIC SENSOR | BURLES BARRY (GB) | 2011-11-24 | — | — | US | disclosed |
| US-8048680-B2 | Holographic sensor | SMART HOLOGRAMS LIMITED (GB) | 2011-11-01 | — | — | US | disclosed |
| US-8048680-B2 | Holographic sensor | SMART HOLOGRAMS LIMITED (GB) | 2011-11-01 | — | — | US | disclosed |
| US-7998412-B2 | Ophthalmic device comprising a holographic sensor | SMART HOLOGRAMS LIMITED (GB) | 2011-08-16 | — | — | US | disclosed |
| US-20090021697-A1 | Ophthalmic Device Comprising a Holographic Sensor | SMART HOLOGRAMS LIMITED (GB) | 2009-01-22 | — | — | US | disclosed |