Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2591725 | 0.78 | — | — | |
| SCHEMBL18249730 | 0.71 | — | — | |
| SCHEMBL11607933 | 0.70 | PKM (0.34) | LTB4RTSHR | |
| SCHEMBL11607935 | 0.70 | ALDH1A1 (0.36) | — | |
| SCHEMBL9769293 | 0.68 | TSHR (0.34) | LTB4RTSHR | |
| SCHEMBL5077054 | 0.68 | TSHR (0.35) | LTB4RTSHR | |
| SCHEMBL15090211 | 0.68 | LTB4R (0.35) | LTB4RTSHR | |
| SCHEMBL4547874 | 0.67 | LTB4R (0.33) | LTB4RTSHR | |
| SCHEMBL14496454 | 0.67 | LTB4R (0.30) | LTB4RTSHR | |
| SCHEMBL12622691 | 0.67 | LTB4R (0.30) | LTB4RTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8168671-B2 | Synthesis of thieno[3,4-b]thiophene, thieno[3,4-b]furan, related compounds and their derivatives and use thereof | THE UNIVERSITY OF CONNECTICUT (US) | 2012-05-01 | — | — | US | disclosed |
| US-20090326187-A1 | SYNTHESIS OF THIENO[3,4-b]THIOPHENE, THIENO[3,4-b]FURAN, RELATED COMPOUNDS AND THEIR DERIVATIVES AND USE THEREOF | THE UNIVERSITY OF CONNECTICUT | 2009-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090326187-A1 | SYNTHESIS OF THIENO[3,4-b]THIOPHENE, THIENO[3,4-b]FURAN, RELATED COMPOUNDS AND THEIR DERIVATIVES AND USE THEREOF | TENT4B, TERB1, CYP4B1 | LTB4R 32/4885TSHR 545/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.