Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 3/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | MYC | P01106 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
| ▸ | TPMT | P51580 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6859659 | 0.86 | EPHX2 (0.54) | EPHX2ALDH1A1KDM4EGAAL3MBTL1 | |
| SCHEMBL2591830 | 0.86 | EPHX2 (0.54) | EPHX2ALDH1A1KDM4EGAAL3MBTL1 | |
| SCHEMBL8028194 | 0.85 | RXRA (0.53) | ACE2KDM4EHSD17B10RXRARARB | |
| SCHEMBL5223897 | 0.85 | EPHX2 (0.50) | ACE2EPHX2ALDH1A1KDM4EGAA | |
| SCHEMBL11427122 | 0.84 | PKM (0.52) | ACE2ALDH1A1KDM4EGAAL3MBTL1 | |
| SCHEMBL1909365 | 0.84 | PKM (0.61) | ALDH1A1L3MBTL1HSD17B10TDP1KMT2A | |
| SCHEMBL14235189 | 0.82 | NR1H4 (0.52) | EPHX2ALDH1A1KDM4EGAAL3MBTL1 | |
| SCHEMBL11423248 | 0.82 | EPHX2 (0.51) | EPHX2ALDH1A1KDM4EGAAL3MBTL1 | |
| SCHEMBL3360458 | 0.82 | EPHX2 (0.51) | ACE2EPHX2ALDH1A1KDM4EGAA | |
| SCHEMBL6439247 | 0.82 | EPHX2 (0.51) | ACE2EPHX2ALDH1A1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105001298-A | Synthesis-separation and purification method for indissolvable polypeptide | SPEC CHEM INDUSTRY INC | 2015-10-28 | — | — | CN | claimed |
| CN-105001307-A | Coupling peptide chain capable of dissolving indissolvable polypeptide and application of the same in separation and purification in liquid chromatogram | SPEC CHEM INDUSTRY INC | 2015-10-28 | — | — | CN | claimed |
| CN-114163162-B | Mineral powder hardening grinding aid and grinding-aid process thereof | 常州坚鹏建材有限公司 | 2022-08-09 | — | — | CN | disclosed |
| CN-114163162-A | Mineral powder hardening grinding aid and grinding-aid process thereof | 常州坚鹏建材有限公司 | 2022-03-11 | — | — | CN | disclosed |
| EP-2766360-B1 | SOLUBLE GUANYLATE CYCLASE ACTIVATORS | BOEHRINGER INGELHEIM INT (DE) | 2017-07-12 | — | — | EP | disclosed |
| US-9670231-B2 | Fused tricyclic amide compounds as multiple kinase inhibitors | BEIGENE, LTD. (KY) | 2017-06-06 | — | — | US | disclosed |
| US-9670231-B2 | Fused tricyclic amide compounds as multiple kinase inhibitors | BEIGENE, LTD. (KY) | 2017-06-06 | — | — | US | disclosed |
| CN-105531269-A | \"inhibitors of nicotinamide phosphoribosyltransferase, compositions, products and uses thereof\ | UNIV DEGLI STUDI DEL PIEMONTE ORIENTALE AMEDEO AVOGADRO | 2016-04-27 | — | — | CN | disclosed |
| CN-105001307-A | Coupling peptide chain capable of dissolving indissolvable polypeptide and application of the same in separation and purification in liquid chromatogram | SPEC CHEM INDUSTRY INC | 2015-10-28 | — | — | CN | disclosed |
| CN-105001298-A | Synthesis-separation and purification method for indissolvable polypeptide | SPEC CHEM INDUSTRY INC | 2015-10-28 | — | — | CN | disclosed |
| CN-104822678-A | Compounds having muscarinic receptor antagonist and beta2 adrenergic receptor agonist activity | CHIESI FARMA SPA | 2015-08-05 | — | — | CN | disclosed |
| US-8815857-B2 | Soluble guanylate cyclase activators | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-08-26 | — | — | US | disclosed |
| US-8815857-B2 | Soluble guanylate cyclase activators | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-08-26 | — | — | US | disclosed |
| US-20130203729-A1 | SOLUBLE GUANYLATE CYCLASE ACTIVATORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-08-08 | — | — | US | disclosed |
| US-20130203729-A1 | SOLUBLE GUANYLATE CYCLASE ACTIVATORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-08-08 | — | — | US | disclosed |
| CN-103209969-A | Functionalised antifouling compounds and use thereof | AGENCY SCIENCE TECH & RES | 2013-07-17 | — | — | CN | disclosed |
| WO-2013025425-A1 | SOLUBLE GUANYLATE CYCLASE ACTIVATORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-02-21 | — | — | WO | disclosed |
| WO-2012055482-A1 | NON-METAL TANNING PROCESS | CLARIANT INTERNATIONAL LTD (CH) | 2012-05-03 | — | — | WO | disclosed |
| WO-2012055483-A1 | NON-METAL TANNING PROCESS | CLARIANT INTERNATIONAL LTD (CH) | 2012-05-03 | — | — | WO | disclosed |
| CN-1215404-A | Non-dendritic backbone piptide carrier | PEPRESEACH A S (DK) | 1999-04-28 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130203729-A1 | SOLUBLE GUANYLATE CYCLASE ACTIVATORS | GUCY1A2, GUCY1A1, GUCY1B1 | ACE2 1818/4885EPHX2 612/4885ALDH1A1 1347/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.