SCHEMBL15857005

SCHEMBL15857005

c1ccc2cc(-c3ccc4c(ccc5cc(-c6cccc7c6sc6ccccc67)ccc54)c3)ccc2c1

nearest known ligand 0.59

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.59
PRKDC P78527 1/20 0.44
S1PR5 Q9H228 13/20 0.44
S1PR4 O95977 10/20 0.44
GSTP1 P09211 1/20 0.40
PARP14 Q460N5 1/20 0.40
HSD17B1 P14061 1/20 0.38
HSD17B2 P37059 1/20 0.38
HDAC4 P56524 1/20 0.38
HDAC2 Q92769 1/20 0.38
HDAC8 Q9BY41 1/20 0.38
GPR84 Q9NQS5 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15893250 0.97 ALOX5 (0.59) ALOX5PRKDCS1PR5S1PR4GSTP1
SCHEMBL17167404 0.96 ALOX5 (0.64) ALOX5PRKDCS1PR5S1PR4GSTP1
SCHEMBL16302997 0.94 ALOX5 (0.66) ALOX5PRKDCS1PR5S1PR4PARP14
SCHEMBL18086206 0.94 ALOX5 (0.66) ALOX5PRKDCS1PR5S1PR4GSTP1
SCHEMBL15188007 0.93 ALOX5 (0.58) ALOX5PRKDCS1PR5S1PR4PARP14
SCHEMBL15857006 0.93 ALOX5 (0.58) ALOX5PRKDCS1PR5S1PR4GSTP1
SCHEMBL18086204 0.93 ALOX5 (0.61) ALOX5PRKDCS1PR5S1PR4GSTP1
SCHEMBL25118633 0.92 ALOX5 (0.54) ALOX5PRKDCS1PR5S1PR4GSTP1
SCHEMBL17268974 0.92 ALOX5 (0.57) ALOX5PRKDCS1PR5S1PR4PARP14
SCHEMBL15893256 0.92 ALOX5 (0.57) ALOX5PRKDCS1PR5S1PR4GSTP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10038152-B2 Organic light-emitting element CANON KABUSHIKI KAISHA (JP) 2018-07-31 US disclosed
US-10038152-B2 Organic light-emitting element CANON KABUSHIKI KAISHA (JP) 2018-07-31 US disclosed
US-9899613-B2 Organic light-emitting element CANON KABUSHIKI KAISHA (JP) 2018-02-20 US disclosed
US-9899613-B2 Organic light-emitting element CANON KABUSHIKI KAISHA (JP) 2018-02-20 US disclosed
EP-2939289-B1 ORGANIC LIGHT-EMITTING ELEMENT CANON KK (JP) 2017-07-26 EP disclosed
US-20150372244-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-12-24 US disclosed
US-20150372244-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-12-24 US disclosed
US-20150357586-A1 ORGANIC LIGHT-EMITTING ELEMENT SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-12-10 US disclosed
US-20150357586-A1 ORGANIC LIGHT-EMITTING ELEMENT SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-12-10 US disclosed
US-20150295188-A1 ORGANIC LIGHT-EMITTING ELEMENT SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-10-15 US disclosed
US-20150295188-A1 ORGANIC LIGHT-EMITTING ELEMENT SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-10-15 US disclosed
WO-2014123238-A1 ORGANIC LIGHT-EMITTING DEVICE CANON KABUSHIKI KAISHA (JP) 2014-08-14 WO disclosed
WO-2014112658-A1 ORGANIC LIGHT-EMITTING ELEMENT CANON KABUSHIKI KAISHA (JP) 2014-07-24 WO disclosed
WO-2014104386-A1 ORGANIC LIGHT-EMITTING ELEMENT CANON KABUSHIKI KAISHA (JP) 2014-07-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10038152-B2 Organic light-emitting element NFE2L2, EML4, LEF1 ALOX5 1144/4885PRKDC 4155/4885S1PR5 4848/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.