SCHEMBL17167404

SCHEMBL17167404

c1ccc2cc(-c3ccc4cc(-c5cccc6c5sc5ccccc56)ccc4c3)ccc2c1

nearest known ligand 0.64

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.64
S1PR5 Q9H228 12/20 0.46
S1PR4 O95977 9/20 0.46
PRKDC P78527 1/20 0.44
GSTP1 P09211 1/20 0.43
PARP14 Q460N5 1/20 0.43
HSD17B1 P14061 1/20 0.41
HSD17B2 P37059 1/20 0.41
HDAC4 P56524 1/20 0.41
HDAC2 Q92769 1/20 0.41
HDAC8 Q9BY41 1/20 0.41
ESR1 P03372 1/20 0.40
ESR2 Q92731 1/20 0.40
GPR3 P46089 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18086206 0.98 ALOX5 (0.66) ALOX5S1PR5S1PR4PRKDCGSTP1
SCHEMBL18086204 0.97 ALOX5 (0.61) ALOX5S1PR5S1PR4PRKDCGSTP1
SCHEMBL25118599 0.96 ALOX5 (0.59) ALOX5S1PR5S1PR4PRKDCGSTP1
SCHEMBL15857005 0.96 ALOX5 (0.59) ALOX5S1PR5S1PR4PRKDCGSTP1
SCHEMBL15857006 0.94 ALOX5 (0.58) ALOX5S1PR5S1PR4PRKDCGSTP1
SCHEMBL12023548 0.94 ALOX5 (0.58) ALOX5S1PR5S1PR4PRKDCGSTP1
SCHEMBL15893256 0.93 ALOX5 (0.57) ALOX5S1PR5S1PR4PRKDCGSTP1
SCHEMBL12023545 0.93 ALOX5 (0.57) ALOX5S1PR5S1PR4PRKDCGSTP1
SCHEMBL17167388 0.93 ALOX5 (0.59) ALOX5S1PR5S1PR4PRKDCGSTP1
SCHEMBL25118600 0.93 ALOX5 (0.56) ALOX5S1PR5S1PR4PRKDCGSTP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10038152-B2 Organic light-emitting element CANON KABUSHIKI KAISHA (JP) 2018-07-31 US disclosed
US-10038152-B2 Organic light-emitting element CANON KABUSHIKI KAISHA (JP) 2018-07-31 US disclosed
US-9899613-B2 Organic light-emitting element CANON KABUSHIKI KAISHA (JP) 2018-02-20 US disclosed
US-9899613-B2 Organic light-emitting element CANON KABUSHIKI KAISHA (JP) 2018-02-20 US disclosed
US-20150372244-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-12-24 US disclosed
US-20150372244-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-12-24 US disclosed
US-20150357586-A1 ORGANIC LIGHT-EMITTING ELEMENT SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-12-10 US disclosed
US-20150357586-A1 ORGANIC LIGHT-EMITTING ELEMENT SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-12-10 US disclosed
US-20150295188-A1 ORGANIC LIGHT-EMITTING ELEMENT SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-10-15 US disclosed
US-20150295188-A1 ORGANIC LIGHT-EMITTING ELEMENT SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-10-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10038152-B2 Organic light-emitting element NFE2L2, EML4, LEF1 ALOX5 1144/4885S1PR5 4848/4885S1PR4 4789/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.