SCHEMBL4549313

SCHEMBL4549313

CC(C)c1ccc2sc3c(-c4ccc(-c5cc6ccccc6c6ccccc56)cc4)cc(C(C)C)cc3c2c1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIM1 P11309 2/20 0.35
PIM2 Q9P1W9 2/20 0.35
METAP2 P50579 1/20 0.34
MAPT P10636 3/20 0.34
RAB9A P51151 2/20 0.34
PAX8 Q06710 1/20 0.34
NOD2 Q9HC29 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
CYP11B1 P15538 1/20 0.33
ALOX5 P09917 1/20 0.33
KIF11 P52732 1/20 0.31
GPR84 Q9NQS5 1/20 0.30
DHODH Q02127 1/20 0.30
TNKS O95271 1/20 0.30
TNKS2 Q9H2K2 1/20 0.30
NPC1 O15118 1/20 0.30
SCN4A P35499 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
GPR35 Q9HC97 1/20 0.30
PFKFB3 Q16875 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4549314 0.86 MCL1 (0.33) PIM1PIM2RAB9AL3MBTL1CYP11B1
SCHEMBL4549340 0.81 ALOX5 (0.49) PIM1PIM2MAPTRAB9APAX8
SCHEMBL25470357 0.79 TNKS (0.48) METAP2MAPTRAB9APAX8NOD2
SCHEMBL10227108 0.79 KIF11 (0.50) PIM1PIM2METAP2MAPTRAB9A
SCHEMBL4549310 0.79 DHODH (0.34) MAPTL3MBTL1CYP11B1ALOX5DHODH
SCHEMBL4549289 0.79 GPR84 (0.37) PIM1PIM2MAPTRAB9AL3MBTL1
SCHEMBL4549320 0.79 CYP11B1 (0.35) MAPTCYP11B1ALOX5GPR84KDM4E
SCHEMBL8281200 0.78 RAB9A (0.40) METAP2MAPTRAB9ANPC1SMN1; SMN2
SCHEMBL4549325 0.78 ESR1 (0.36) PIM1PIM2MAPTCYP11B1ALOX5
SCHEMBL10127923 0.77 MAPT (0.31) PIM1PIM2MAPTPFKFB3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9406889-B2 Phenanthrene compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-08-02 US disclosed
US-9406889-B2 Phenanthrene compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-08-02 US disclosed
US-20150171333-A1 Phenanthrene Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-06-18 US disclosed
US-20150171333-A1 Phenanthrene Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-06-18 US disclosed
US-8968888-B2 Phenanthrene compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-03-03 US disclosed
US-8968888-B2 Phenanthrene compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-03-03 US disclosed
US-20120104369-A1 Phenanthrene Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-05-03 US disclosed
US-20120104369-A1 Phenanthrene Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-05-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120104369-A1 Phenanthrene Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device MC1R, NR2E3, RPS19 PIM1 2437/4885PIM2 3330/4885METAP2 4303/4885
US-20150171333-A1 Phenanthrene Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device MC1R, NR2E3, RPS19 PIM1 2437/4885PIM2 3330/4885METAP2 4303/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.