SCHEMBL4549434

SCHEMBL4549434

c1ccc(C2(c3ccccc3)c3ccccc3-c3ccc(-c4ccc5cc(-c6ccc(-c7cccc8c7oc7ccccc78)cc6)c6ccccc6c5c4)cc32)cc1

nearest known ligand 0.43

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.43
PRKDC P78527 6/20 0.34
GGPS1 O95749 1/20 0.34
PTGES2 Q9H7Z7 1/20 0.32
CDC14B O60729 2/20 0.30
CDC14A Q9UNH5 2/20 0.30
PIK3CD O00329 1/20 0.30
PIK3CB P42338 1/20 0.30
PLA2G10 O15496 1/20 0.30
PLA2G2A P14555 1/20 0.30
PLA2G4A P47712 1/20 0.30
PDK2 Q15119 1/20 0.30
ATM Q13315 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4549437 0.94 ALOX5 (0.46) ALOX5PRKDCGGPS1PTGES2CDC14B
SCHEMBL4549387 0.89 ALOX5 (0.49) ALOX5PRKDCGGPS1PTGES2CDC14B
SCHEMBL18086161 0.88 ALOX5 (0.54) ALOX5PRKDCGGPS1PTGES2CDC14B
SCHEMBL18086151 0.87 ALOX5 (0.51) ALOX5PRKDCGGPS1PTGES2CDC14B
SCHEMBL20277499 0.85 ALOX5 (0.57) ALOX5PRKDCGGPS1PTGES2CDC14B
SCHEMBL4549432 0.85 ALOX5 (0.44) ALOX5PRKDCGGPS1PTGES2PIK3CD
SCHEMBL25052981 0.85 ALOX5 (0.49) ALOX5PRKDCGGPS1PTGES2CDC14B
SCHEMBL4549381 0.85 ALOX5 (0.51) ALOX5PRKDCGGPS1PTGES2PIK3CD
SCHEMBL22061692 0.84 ALOX5 (0.40) ALOX5PRKDCGGPS1PTGES2PIK3CD
SCHEMBL4549409 0.84 MAPK1 (0.32) ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9406889-B2 Phenanthrene compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-08-02 US disclosed
US-9406889-B2 Phenanthrene compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-08-02 US disclosed
US-20150171333-A1 Phenanthrene Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-06-18 US disclosed
US-20150171333-A1 Phenanthrene Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-06-18 US disclosed
US-8968888-B2 Phenanthrene compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-03-03 US disclosed
US-8968888-B2 Phenanthrene compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-03-03 US disclosed
US-20120104369-A1 Phenanthrene Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-05-03 US disclosed
US-20120104369-A1 Phenanthrene Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-05-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120104369-A1 Phenanthrene Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device MC1R, NR2E3, RPS19 ALOX5 3393/4885PRKDC 4132/4885GGPS1 1183/4885
US-20150171333-A1 Phenanthrene Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device MC1R, NR2E3, RPS19 ALOX5 3393/4885PRKDC 4132/4885GGPS1 1183/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.