SCHEMBL455028

SCHEMBL455028

COc1ccc2ccccc2c1OC(C)=O

nearest known ligand 0.58

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.53
MTNR1A P48039 2/20 0.50
MTNR1B P49286 2/20 0.50
KDM4E B2RXH2 2/20 0.49
ALDH1A1 P00352 2/20 0.49
POLB P06746 2/20 0.49
MEN1 O00255 1/20 0.49
NPC1 O15118 1/20 0.49
MAPK1 P28482 1/20 0.49
RAB9A P51151 1/20 0.49
KMT2A Q03164 1/20 0.49
NCEH1 Q6PIU2 5/20 0.48
HTT P42858 2/20 0.47
CYP1A2 P05177 1/20 0.47
CYP3A4 P08684 1/20 0.47
CYP2C9 P11712 1/20 0.47
CYP2C19 P33261 1/20 0.47
HPGD P15428 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29357471 1.00 MAPT (0.53) MAPTMTNR1AMTNR1BKDM4EALDH1A1
SCHEMBL9488962 0.90 HTT (0.54) MAPTKDM4EALDH1A1POLBMAPK1
SCHEMBL27489224 0.87 NCEH1 (0.49) MAPTMTNR1AMTNR1BALDH1A1MEN1
SCHEMBL11865826 0.85 MAPT (0.51) MAPTMTNR1AMTNR1BKDM4EALDH1A1
SCHEMBL10590588 0.83 HTT (0.51) MAPTKDM4EALDH1A1POLBNCEH1
SCHEMBL819552 0.83 MAPT (0.49) MAPTMTNR1AMTNR1BKDM4EALDH1A1
SCHEMBL16237145 0.82 MAPT (0.71) MAPTMTNR1AMTNR1BKDM4EALDH1A1
SCHEMBL4225247 0.82 NCEH1 (0.48) MTNR1AMTNR1BKDM4EALDH1A1MAPK1
SCHEMBL28485377 0.81 L3MBTL1 (0.48) MAPTMTNR1AMTNR1BNPC1RAB9A
SCHEMBL10895815 0.81 HTT (0.49) MAPTKDM4EALDH1A1POLBMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2785323-B1 AGENT AND METHOD FOR COLOURING KERATIN FIBRES GW COSMETICS GMBH (AT) 2018-07-18 EP claimed
US-9125842-B2 Agent and method for coloring keratin fibers GW COSMETICS GMBH (AT) 2015-09-08 US claimed
US-20140310888-A1 AGENT AND METHOD FOR COLORING KERATIN FIBERS GW COSMETICS GMBH (AT) 2014-10-23 US claimed
EP-2785323-A2 AGENT AND METHOD FOR COLOURING KERATIN FIBRES GW Cosmetics GmbH (AT) 2014-10-08 EP claimed
WO-2013078492-A2 AGENT AND METHOD FOR COLOURING KERATIN FIBRES GW COSMETICS GMBH (AT) 2013-06-06 WO claimed
US-12485076-B2 Liquid hair dye composition KAO CORPORATION (JP) 2025-12-02 US disclosed
EP-3229919-B1 COMPOSITION AND PROCEDURE FOR TREATING KERATIN-CONTAINING FIBERS WITH FLASH EVAPORATION HENKEL AG & CO KGAA (DE) 2024-03-13 EP disclosed
US-20220151897-A1 LIQUID HAIR DYE COMPOSITION KAO CORPORATION (JP) 2022-05-19 US disclosed
EP-3943161-A1 LIQUID HAIR DYE COMPOSITION Kao Corporation (JP) 2022-01-26 EP disclosed
CN-113613732-A Liquid hair dye composition 花王株式会社 2021-11-05 CN disclosed
WO-2020188936-A1 LIQUID HAIR DYE COMPOSITION 花王株式会社 2020-09-24 WO disclosed
US-10342751-B2 Double-chamber pouch for dyeing human hair HENKEL AG & CO. KGAA (DE) 2019-07-09 US disclosed
WO-2012052198-A1 PROCESS FOR PRODUCING A COLORANT FOR KERATIN FIBRES HENKEL AG & CO. KGAA (DE) 2012-04-26 WO disclosed
WO-2012038114-A2 COLOUR PRESERVATION BY MEANS OF CONDITIONING AGENTS CONTAINING REDUCING AGENTS HENKEL AG & CO. KGAA (DE) 2012-03-29 WO disclosed
WO-2012031796-A2 AGENTS FOR COLOURING KERATINIC FIBRES WITH CATIONIC DERIVATIVES OF 1-(2,5-DIHYDROXYPHENYL)PYRIDINIUM HENKEL AG & CO. KGAA (DE) 2012-03-15 WO disclosed
EP-2324811-A2 Foam-like dye Henkel AG & Co. KGaA (DE) 2011-05-25 EP disclosed
WO-2011051087-A1 TINTING AGENT HENKEL AG & CO. KGAA (DE) 2011-05-05 WO disclosed
EP-2308455-A2 Foaming dye II Henkel AG & Co. KGaA (DE) 2011-04-13 EP disclosed
EP-2301520-A2 Oxidative dye Henkel AG & Co. KGaA (DE) 2011-03-30 EP disclosed
US-4515970-A Process for preparation of alkanoic acids SOCIETE FRANCAISE HOECHST (FR) 1985-05-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12485076-B2 Liquid hair dye composition S100B, HLA-B, LDHB MAPT 3771/4885MTNR1A 2787/4885MTNR1B 1410/4885
US-20220151897-A1 LIQUID HAIR DYE COMPOSITION S100B, HLA-B, LDHB MAPT 3771/4885MTNR1A 2787/4885MTNR1B 1410/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.