SCHEMBL819552

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL28017827	0.89	TYMS (0.46)	MAPTHPGDCYP1A1CYP1B1NCEH1
	SCHEMBL29277282	0.88	CYP1A1 (0.47)	MAPTMTNR1AMTNR1BCYP1A2CYP3A4
	SCHEMBL19125087	0.84	TYMS (0.39)	MAPTCYP1A2CYP2C9CYP2C19HPGD
	SCHEMBL455028	0.83	MAPT (0.53)	MAPTMTNR1AMTNR1BCYP1A2CYP3A4
	SCHEMBL29357471	0.83	MAPT (0.53)	MAPTMTNR1AMTNR1BCYP1A2CYP3A4
	SCHEMBL30226686	0.82	HTR1A (0.43)	CYP3A4KDM4EL3MBTL1ALDH1A1HTT
	SCHEMBL27947715	0.81	TSHR (0.43)	MAPTCYP1A2HPGDKDM4ECYP1A1
	SCHEMBL11865826	0.81	MAPT (0.51)	MAPTMTNR1AMTNR1BCYP1A2CYP3A4
	SCHEMBL30226804	0.81	TYMS (0.50)	MAPTCYP1A2CYP3A4CYP2C9HPGD
	SCHEMBL68670	0.81	TYMS (0.50)	MAPTCYP1A2CYP3A4CYP2C9HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.