Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 6/20 | 0.39 |
| ▸ | ABAT | P80404 | 1/20 | 0.37 |
| ▸ | PNMT | P11086 | 1/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.37 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | LOX | P28300 | 1/20 | 0.34 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15047147 | 0.80 | CSNK2A1 (0.47) | HRH3LOXL2PNMTTAAR1LOX | |
| SCHEMBL15047137 | 0.80 | CSNK2A1 (0.43) | HRH3LOXL2PNMTCYP2A6TAAR1 | |
| SCHEMBL63659 | 0.77 | HRH3 (0.46) | HRH3LOXL2ABATPNMTENPP2 | |
| SCHEMBL29760412 | 0.77 | HRH3 (0.46) | HRH3LOXL2ABATPNMTENPP2 | |
| SCHEMBL2666219 | 0.76 | TRPA1 (0.43) | CYP2A6TAAR1 | |
| SCHEMBL4550353 | 0.76 | LOXL2 (0.41) | HRH3LOXL2TAAR1LOX | |
| SCHEMBL1696358 | 0.71 | CSNK2A1 (0.49) | HRH3LOXL2ABATPNMTENPP2 | |
| SCHEMBL14325143 | 0.71 | HRH3 (0.58) | HRH3LOXL2ABATST14TAAR1 | |
| SCHEMBL2666168 | 0.70 | DHFR (0.38) | CYP2A6 | |
| SCHEMBL13443568 | 0.70 | CSNK2A1 (0.47) | HRH3LOXL2ABATPNMTENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2066623-B1 | PROCESS FOR PRODUCING 1-(3,4-DICHLOROBENZYL)-5-OCTYLBIGUANIDE OR A SALT THEREOF | OTSUKA PHARMA CO LTD (JP) | 2013-06-19 | — | — | EP | disclosed |