Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | MGAM | O43451 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | SI | P14410 | 1/20 | 0.49 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10548869 | 0.75 | ALDH1A1 (0.50) | MAOBMGAMGAASIMGAM2 | |
| SCHEMBL1569126 | 0.74 | LMNA (0.43) | LMNAALDH1A1TDP1L3MBTL1KMT2A | |
| SCHEMBL11033865 | 0.73 | ALDH1A1 (0.49) | MAOBMGAMGAASIMGAM2 | |
| SCHEMBL4541518 | 0.73 | MAOB (0.50) | LMNAMAOBMGAMGAASI | |
| SCHEMBL16180249 | 0.73 | MAOB (0.54) | MAOBMGAMGAASIMGAM2 | |
| SCHEMBL1287837 | 0.73 | ALDH1A1 (0.74) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL30535903 | 0.73 | ALDH1A1 (0.74) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL15318818 | 0.73 | ALDH1A1 (0.57) | MAOBMGAMGAASIMGAM2 | |
| SCHEMBL3026474 | 0.72 | MGAM (0.55) | LMNAMAOBMGAMGAASI | |
| SCHEMBL220611 | 0.72 | MGAM (0.55) | LMNAMAOBMGAMGAASI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7629463-B2 | Ortho-heterocyclic substituted aryl amides for controlling invertebrate pests | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-12-08 | — | — | US | disclosed |
| CN-100506817-C | Ortho-heterocyclic substituted arylamides for controlling invertebrate pests | DU PONT (US) | 2009-07-01 | — | — | CN | disclosed |
| US-20080132524-A1 | Ortho-heterocyclic substituted aryl amides for controlling invertebrate pests | CLARK DAVID ALAN | 2008-06-05 | — | — | US | disclosed |
| US-7375232-B2 | Ortho-heterocyclic substituted aryl amides for controlling invertebrate pests | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-05-20 | — | — | US | disclosed |
| EP-1417204-B1 | ORTHO-HETEROCYCLIC SUBSTITUTED ARYL AMIDES FOR CONTROLLING INVERTEBRATE PESTS | DU PONT (US) | 2006-01-18 | — | — | EP | disclosed |
| US-20040242645-A1 | Ortho-heterocyclic substituted aryl amides for controlling invertebrate pests | E. I. DU PONT DE NEMOURS AND COMPANY | 2004-12-02 | — | — | US | disclosed |
| CN-1543460-A | Ortho-heterocyclic substituted aryl amides for controlling invertebrate pests | ��Ļ���Ű˾ | 2004-11-03 | — | — | CN | disclosed |
| EP-1417204-A1 | ORTHO-HETEROCYCLIC SUBSTITUTED ARYL AMIDES FOR CONTROLLING INVERTEBRATE PESTS | E. I. du Pont de Nemours and Company (US) | 2004-05-12 | — | — | EP | disclosed |
| WO-2003016304-A1 | ORTHO-HETEROCYCLIC SUBSTITUTED ARYL AMIDES FOR CONTROLLING INVERTEBRATE PESTS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2003-02-27 | — | — | WO | disclosed |
| US-4810282-A | 3-ORTHO-(ISOXAZOLYL,ISOTHIAZOLYL, PYRAZOLYL,THIADIAZOLYL, OXADIAZOLYL AND TRIAZOLYL BENZENESULFONUREYLENE-1,2,4-TRIAZOLES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-03-07 | — | — | US | disclosed |
| EP-0083975-B1 | HERBICIDAL SULFONAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-11-19 | — | — | EP | disclosed |
| US-4695311-A | Herbicidal sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-09-22 | — | — | US | disclosed |
| US-4606755-A | Herbicidal sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1986-08-19 | — | — | US | disclosed |
| US-4511392-A | N--/PYRIMIDIN-2-YLAMINOCARBENYL/-HETERO-SUBSTITUETED BENZENSESULFO | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-04-16 | — | — | US | disclosed |
| EP-0083975-A2 | Herbicidal sulfonamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1983-07-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080132524-A1 | Ortho-heterocyclic substituted aryl amides for controlling invertebrate pests | AOC2, DDT, CBR3 | LMNA 4791/4885MAOB 269/4885MGAM 4630/4885 |
| US-20040242645-A1 | Ortho-heterocyclic substituted aryl amides for controlling invertebrate pests | AOC2, OLA1, AOC3 | LMNA 3892/4885MAOB 776/4885MGAM 4558/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.