SCHEMBL898809

SCHEMBL898809

CCCCCCCCCCCCCCCCCCCCCCNC(CO)C(O)CCCCCCCCCCCCCCC

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.57
KMT2A Q03164 1/20 0.57
KDM4E B2RXH2 2/20 0.55
ASAH1 Q13510 1/20 0.55
ALDH1A1 P00352 1/20 0.55
SPHK1 Q9NYA1 3/20 0.52
CYP2D6 P10635 2/20 0.52
LMNA P02545 2/20 0.52
GMNN O75496 1/20 0.52
POLB P06746 1/20 0.52
THPO P40225 1/20 0.52
MTOR P42345 1/20 0.52
BLM P54132 1/20 0.52
TP53 P04637 1/20 0.52
CYP1A2 P05177 1/20 0.52
CYP3A4 P08684 1/20 0.52
MAPT P10636 1/20 0.52
CETP P11597 1/20 0.52
HTT P42858 1/20 0.52
UBE2N P61088 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28696485 1.00 MEN1 (0.57) MEN1KMT2AKDM4EASAH1ALDH1A1
SCHEMBL15239749 1.00 MEN1 (0.57) MEN1KMT2AKDM4EASAH1ALDH1A1
SCHEMBL4432269 1.00 MEN1 (0.57) MEN1KMT2AKDM4EASAH1ALDH1A1
SCHEMBL30368691 1.00 MEN1 (0.57) MEN1KMT2AKDM4EASAH1ALDH1A1
SCHEMBL2727470 1.00 MEN1 (0.57) MEN1KMT2AKDM4EASAH1ALDH1A1
SCHEMBL30432362 1.00 MEN1 (0.57) MEN1KMT2AKDM4EASAH1ALDH1A1
SCHEMBL5718656 1.00 MEN1 (0.57) MEN1KMT2AKDM4EASAH1ALDH1A1
SCHEMBL4550651 0.98 MEN1 (0.54) MEN1KMT2AKDM4EASAH1ALDH1A1
SCHEMBL6237363 0.91 KDM4E (0.67) MEN1KMT2AKDM4EASAH1ALDH1A1
SCHEMBL8815031 0.91 KDM4E (0.67) MEN1KMT2AKDM4EASAH1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1093809-B1 Cosmetic compositions containing a vinyldimethicone/dimethicone copolymer and a conditioning agent, and their uses OREAL (FR) 2006-10-25 EP claimed
EP-3793512-B1 METHODS FOR BOOSTING UVA PHOTO-PROTECTION USING ANTIOXIDANTS OREAL (FR) 2024-02-21 EP disclosed
US-20240009108-A1 COSMETIC COMPOSITION, USE OF A COSMETIC COMPOSITION AND PROCESS OF MANUFACTURING A COSMETIC COMPOSITION L'OREAL (FR) 2024-01-11 US disclosed
US-11337906-B2 Hair care and conditioning compositions L'OREAL (FR) 2022-05-24 US disclosed
US-20220016013-A1 COMPOSITION COMPRISING AN ALKOXYSILANE, A FATTY ESTER AND A SILICONE, AND COSMETIC USE THEREOF L'OREAL (FR) 2022-01-20 US disclosed
US-10729633-B2 Methods for boosting UVA photo-protection using antioxidants L'OREAL (FR) 2020-08-04 US disclosed
US-10722449-B2 Cosmetic composition comprising amino silicones, cationic surfactants and specific esters and a process for a cosmetic treatment L'OREAL (FR) 2020-07-28 US disclosed
US-20200206111-A1 HAIR CARE AND CONDITIONING COMPOSITIONS L'OREAL (FR) 2020-07-02 US disclosed
US-20200206112-A1 HAIR COLORING COMPOSITIONS AND METHODS OF USE L'OREAL (FR) 2020-07-02 US disclosed
US-10653611-B2 Hair care composition comprising amino silicone, fatty alcohol and paraffin oil L'OREAL (FR) 2020-05-19 US disclosed
WO-2012095398-A2 DYEING OR LIGHTENING PROCESS USING A COMPOSITION RICH IN FATTY SUBSTANCES COMPRISING A SOLID ALCOHOL AND A SOLID ESTER, COMPOSITIONS AND DEVICE L'OREAL (FR) 2012-07-19 WO disclosed
WO-2012095394-A2 PROCESS FOR DYEING OR LIGHTENING KERATIN FIBRES IN TWO PARTS, USING AN OIL-RICH ALKALINE DIRECT EMULSION BASED ON A SOLID NONIONIC SURFACTANT WITH AN HLB RANGING FROM 1.5 TO 10 L'OREAL (FR) 2012-07-19 WO disclosed
WO-2012095395-A2 PROCESS FOR DYEING OR LIGHTENING KERATIN FIBRES IN TWO PARTS, USING AN OIL-RICH DIRECT EMULSION BASED ON A SOLID FATTY ALCOHOL AND ON OILS OF DIFFERENT POLARITY L'OREAL (FR) 2012-07-19 WO disclosed
WO-2012055811-A1 COSMETIC COMPOSITION COMPRISING A FATTY-CHAIN ALKOXYSILANE AND A CATIONIC OR NONIONIC SURFACTANT. L'OREAL (FR) 2012-05-03 WO disclosed
WO-2012055809-A1 COSMETIC COMPOSITION COMPRISING A FATTY-CHAIN ALKOXYSILANE, AN ANIONIC SURFACTANT AND A NONIONIC, AMPHOTERIC OR ZWITTERIONIC SURFACTANT L'OREAL (FR) 2012-05-03 WO disclosed
WO-2012055807-A1 COSMETIC COMPOSITION COMPRISING A FATTY-CHAIN ALKOXYSILANE AND A CATIONIC POLYMER L'OREAL (FR) 2012-05-03 WO disclosed
WO-2012042019-A2 PROCESS FOR TREATING KERATIN FIBRES USING AT LEAST ONE SULFUREOUS REDUCING AGENT, AT LEAST ONE CATIONIC POLYMER AND AT LEAST ONE MERCAPTOSILOXANE. L'OREAL (FR) 2012-04-05 WO disclosed
US-20060140889-A1 Affinity proteins for controlled application of cosmetic substances L-MABS B.V. (US) 2006-06-29 US disclosed
US-20060120984-A1 Cosmetic composition comprising at least one silicone copolymer and at least one conditioner, and uses thereof L'OREAL S.A. 2006-06-08 US disclosed
EP-1470824-A1 Affinity proteins for controlled application of cosmetic substances L-MAbs B.V. (NL) 2004-10-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060120984-A1 Cosmetic composition comprising at least one silicone copolymer and at least one conditioner, and uses thereof KRT18, CUTA, DSG1 MEN1 1388/4885KMT2A 609/4885KDM4E 838/4885
US-10722449-B2 Cosmetic composition comprising amino silicones, cationic surfactants and specific esters and a process for a cosmetic treatment KRT18, CUTA, LAGE3 MEN1 2488/4885KMT2A 1128/4885KDM4E 886/4885
US-10653611-B2 Hair care composition comprising amino silicone, fatty alcohol and paraffin oil KRT18, CUTA, AADAT MEN1 2577/4885KMT2A 397/4885KDM4E 636/4885
US-20240009108-A1 COSMETIC COMPOSITION, USE OF A COSMETIC COMPOSITION AND PROCESS OF MANUFACTURING A COSMETIC COMPOSITION CUTA, TRPC7, PARN MEN1 727/4885KMT2A 3496/4885KDM4E 3936/4885
US-11337906-B2 Hair care and conditioning compositions POLR1C, CUTA, DPM1 MEN1 2719/4885KMT2A 3291/4885KDM4E 2880/4885
US-20200206111-A1 HAIR CARE AND CONDITIONING COMPOSITIONS POLR1C, CUTA, DPM1 MEN1 2719/4885KMT2A 3291/4885KDM4E 2880/4885
US-20200206112-A1 HAIR COLORING COMPOSITIONS AND METHODS OF USE SGMS1, PHOSPHO1, SGMS2 MEN1 3006/4885KMT2A 2651/4885KDM4E 3783/4885
US-20060140889-A1 Affinity proteins for controlled application of cosmetic substances CUTA, APMAP, HSPBP1 MEN1 3879/4885KMT2A 4286/4885KDM4E 4662/4885
US-20220016013-A1 COMPOSITION COMPRISING AN ALKOXYSILANE, A FATTY ESTER AND A SILICONE, AND COSMETIC USE THEREOF KRT18, CUTA, FASN MEN1 1743/4885KMT2A 318/4885KDM4E 207/4885
US-10729633-B2 Methods for boosting UVA photo-protection using antioxidants PRDX3, CUTA, PRDX2 MEN1 4505/4885KMT2A 2895/4885KDM4E 3227/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.