Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13761744 | 1.00 | SMN1; SMN2 (0.33) | SMN1; SMN2CA1CA2MMP8CA14 | |
| SCHEMBL10040223 | 0.83 | ALDH1A1 (0.38) | MMP8ALDH1A1 | |
| SCHEMBL13448432 | 0.78 | — | — | |
| SCHEMBL4550793 | 0.78 | GABRR1 (0.37) | ALDH1A1 | |
| SCHEMBL4550889 | 0.78 | GABRR1 (0.37) | ALDH1A1 | |
| SCHEMBL13448433 | 0.78 | — | — | |
| SCHEMBL14948713 | 0.77 | ESRRB (0.43) | ALDH1A1 | |
| SCHEMBL17236358 | 0.77 | SMN1; SMN2 (0.39) | SMN1; SMN2CA1CA2MMP8CA14 | |
| SCHEMBL5539779 | 0.77 | SMN1; SMN2 (0.39) | SMN1; SMN2CA1CA2MMP8CA14 | |
| SCHEMBL19143548 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3216798-A2 | KETOLIDE COMPOUNDS | Wockhardt Limited (IN) | 2017-09-13 | — | — | EP | disclosed |
| EP-2673285-B1 | KETOLIDE COMPOUNDS | WOCKHARDT LTD (IN) | 2017-07-19 | — | — | EP | disclosed |
| US-20160083412-A1 | KETOLIDE COMPOUNDS | WOCKHARDT LIMITED (IN) | 2016-03-24 | — | — | US | disclosed |
| US-9175031-B2 | Ketolide compounds | WOCKHARDT LIMITED (IN) | 2015-11-03 | — | — | US | disclosed |
| WO-2012076989-A1 | KETOLIDE COMPOUNDS | WOCKHARDT LIMITED (IN) | 2012-06-14 | — | — | WO | disclosed |
| US-8168648-B2 | Camptothecin derivatives and uses thereof | TAIWAN LIPOSOME CO., LTD. (TW) | 2012-05-01 | — | — | US | disclosed |
| US-20100227877-A1 | NEW CAMPTOTHECIN DERIVATIVES AND USES THEREOF | TAIWAN LIPOSOME CO. LTD. (TW) | 2010-09-09 | — | — | US | disclosed |
| US-7271185-B2 | Optically active azole derivative and process for producing the same | MITSUI CHEMICALS, INC. (JP) | 2007-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100227877-A1 | NEW CAMPTOTHECIN DERIVATIVES AND USES THEREOF | LDHA, LDHB, TOP2A | SMN1; SMN2 4581/4885CA1 1731/4885CA2 975/4885 |
| US-20160083412-A1 | KETOLIDE COMPOUNDS | AKR1C3, AKR1D1, AKR1C1 | SMN1; SMN2 4837/4885CA1 2502/4885CA2 1052/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.