Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methylpiperazine SCHEMBL4565823 | 1.00 | MAPK1 (0.47) | MAPK1MEN1KMT2AMAPTCYP3A4 | |
| SCHEMBL4268093 | 0.87 | MITF (0.48) | MAPK1MEN1KMT2AMAPTCYP3A4 | |
| Methylpiperazine SCHEMBL4551702 | 0.86 | MAPT (0.44) | MAPK1MEN1KMT2AMAPTCYP3A4 | |
| SCHEMBL4270390 | 0.75 | MEN1 (0.47) | MAPK1MEN1KMT2AMAPTHTT | |
| SCHEMBL4266901 | 0.74 | RAB9A (0.48) | MAPK1MEN1KMT2AMAPTCYP3A4 | |
| SCHEMBL4419566 | 0.73 | CES1 (0.37) | MEN1KMT2AMAPTCYP3A4RAB9A | |
| SCHEMBL4278133 | 0.73 | L3MBTL1 (0.51) | RAB9AMITFHSP90AA1KDM4EHSD17B10 | |
| SCHEMBL4264174 | 0.71 | ESR1 (0.50) | MAPK1MEN1KMT2AMAPTRAB9A | |
| SCHEMBL4551139 | 0.71 | ESR1 (0.50) | MAPK1MEN1KMT2AMAPTRAB9A | |
| Pyrrolidine SCHEMBL4264339 | 0.71 | MITF (0.41) | MAPK1MEN1KMT2AMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009110002-A1 | NOVEL EFFLUX PUMP INHIBITORS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2009-09-11 | — | — | WO | claimed |
| WO-2009110002-A1 | NOVEL EFFLUX PUMP INHIBITORS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2009-09-11 | — | — | WO | disclosed |