Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | EYA2 | O00167 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | ACE | P12821 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL1081463 | 0.88 | LMNA (0.44) | ALDH1A1LMNAKDM4EKMT2ASMN1; SMN2 | |
| Acrylic Acid SCHEMBL3891399 | 0.86 | LMNA (0.59) | ALDH1A1LMNAKDM4EKMT2ASMN1; SMN2 | |
| Acetic Acid SCHEMBL2866049 | 0.84 | KDM4E (0.38) | ALDH1A1LMNAKDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL5954388 | 0.82 | KDM4E (0.37) | ALDH1A1LMNAKDM4EKMT2ASMN1; SMN2 | |
| Acetic Acid SCHEMBL1181677 | 0.81 | ALDH1A1 (0.39) | ALDH1A1LMNAFFAR3LCKFYN | |
| Acetic Acid SCHEMBL1077081 | 0.81 | ALDH1A1 (0.39) | ALDH1A1LMNAKDM4EKMT2ASMN1; SMN2 | |
| Bicarbonate SCHEMBL3326122 | 0.81 | ALDH1A1 (0.39) | ALDH1A1LMNAKDM4EKMT2ASMN1; SMN2 | |
| Lactic Acid SCHEMBL5529387 | 0.80 | TP53 (0.50) | ALDH1A1LMNAKDM4EKMT2ASMN1; SMN2 | |
| Methyl Alcohol SCHEMBL28949472 | 0.79 | ALDH1A1 (0.35) | ALDH1A1KDM4EKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL431521 | 0.79 | TDP1 (0.55) | ALDH1A1LMNAKDM4EKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0569074-B1 | Method of preparing an aqueous solid particle dispersion of a photographically useful compound | AGFA GEVAERT NV (BE) | 1998-10-14 | — | — | EP | claimed |
| EP-0569074-A1 | Method of preparing an aqueous solid particle dispersion of a photographically useful compound | AGFA-GEVAERT N.V. (BE) | 1993-11-10 | — | — | EP | claimed |
| CN-108440303-B | High-purity triallyl ammonium chloride and preparation method thereof | 山东聚发生物科技有限公司 | 2021-04-02 | — | — | CN | disclosed |
| CN-108440303-A | A kind of high-purity triallylammonium chloride and preparation method thereof | 山东聚发生物科技有限公司 | 2018-08-24 | — | — | CN | disclosed |
| US-8664400-B2 | Triphenylamine derivatives useful as fluorophores in biology, in particular for two-photon microscopy | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2014-03-04 | — | — | US | disclosed |
| US-20090314990-A1 | NOVEL TRIPHENYLAMINE DERIVATIVES USEFUL AS FLUOROPHORES IN BIOLOGY, IN PARTICULAR FOR TWO-PHOTON MICROSCOPY | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2009-12-24 | — | — | US | disclosed |
| EP-0587230-B1 | Photographic element containing a filter dye for rapid processing applications | AGFA GEVAERT (BE) | 2003-11-26 | — | — | EP | disclosed |
| EP-0587229-B1 | Photographic element containing a filter dye for rapid processing applications | AGFA GEVAERT (BE) | 2002-05-08 | — | — | EP | disclosed |
| EP-0656401-B1 | New dyes for use in diverse applications | AGFA GEVAERT NV (BE) | 2001-09-26 | — | — | EP | disclosed |
| EP-0786497-B1 | Dyes for use in diverse applications | AGFA GEVAERT NV (BE) | 1999-09-01 | — | — | EP | disclosed |
| US-5919610-A | Dyes for use in diverse applications | AGFA-GEVAERT, N.V. (BE) | 1999-07-06 | — | — | US | disclosed |
| EP-0781816-A1 | New dyes for use in diverse applications | AGFA-GEVAERT N.V. (BE) | 1997-07-02 | — | — | EP | disclosed |
| US-5502205-A | Dyes for use in diverse applications | AGFA-GEVAERT N.V. (BE) | 1996-03-26 | — | — | US | disclosed |
| US-5478708-A | New dyes for use in diverse applications | AGFA-GEVAERT, N.V. (BE) | 1995-12-26 | — | — | US | disclosed |
| EP-0656401-A2 | New dyes for use in diverse applications | AGFA-GEVAERT N.V. (BE) | 1995-06-07 | — | — | EP | disclosed |
| US-5380634-A | X-ray, quick processing | AGFA-GEVAERT, N.V. (BE) | 1995-01-10 | — | — | US | disclosed |
| US-5344749-A | X-ray photographic material, amide group on methine chain | AGFA-GEVAERT, N.R. (BE) | 1994-09-06 | — | — | US | disclosed |
| EP-0587229-A2 | Filter dyes for rapid processing applications | AGFA-GEVAERT N.V. (BE) | 1994-03-16 | — | — | EP | disclosed |
| EP-0587230-A2 | Filter dyes for rapid processing applications | AGFA-GEVAERT N.V. (BE) | 1994-03-16 | — | — | EP | disclosed |
| EP-0586748-A1 | Filter dyes for rapid processing applications | AGFA-GEVAERT N.V. (BE) | 1994-03-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090314990-A1 | NOVEL TRIPHENYLAMINE DERIVATIVES USEFUL AS FLUOROPHORES IN BIOLOGY, IN PARTICULAR FOR TWO-PHOTON MICROSCOPY | TERB1, TRDMT1, TARBP1 | ALDH1A1 4561/4885LMNA 826/4885KDM4E 3891/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.