⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14842441 | 0.85 | TAAR1 (0.31) | — | |
| SCHEMBL63751 | 0.84 | — | — | |
| SCHEMBL15008845 | 0.81 | TYR (0.39) | — | |
| SCHEMBL22095186 | 0.81 | — | — | |
| SCHEMBL1476654 | 0.80 | ALDH1A1 (0.40) | — | |
| SCHEMBL3831752 | 0.80 | MCL1 (0.41) | — | |
| SCHEMBL58401 | 0.80 | GABRA1 (0.33) | — | |
| SCHEMBL15939878 | 0.80 | CA1 (0.35) | — | |
| SCHEMBL1477884 | 0.80 | MPO (0.33) | — | |
| SCHEMBL28336992 | 0.80 | TYR (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 113 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023076259-A1 | TRIAZOLOPYRIDAZINE COMPOUNDS USEFUL AS RAC1 INHIBITORS | REVERE PHARMACEUTICALS (US) | 2023-05-04 | — | — | WO | claimed |
| CN-101189230-A | Heterocyclic antiviral compounds | ROCHE PALO ALTO LLC (CH) | 2008-05-28 | — | — | CN | claimed |
| US-7326705-B2 | Heterocyclic sodium/proton exchange inhibitors and method | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-02-05 | — | — | US | claimed |
| EP-1879885-A1 | HETEROCYCLIC ANTIVIRAL COMPOUNDS | F. Hoffmann-Roche AG (CH) | 2008-01-23 | — | — | EP | claimed |
| WO-2006117306-A1 | HETEROCYCLIC ANTIVIRAL COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2006-11-09 | — | — | WO | claimed |
| US-20050137216-A1 | Heterocyclic sodium/proton exchange inhibitors and method | AHMAD SALEEM (US) | 2005-06-23 | — | — | US | claimed |
| CN-1468232-A | Heterocyclic sodium/proton exchange inhibitors and method | ����˹�ж�-����˹˹������˾ | 2004-01-14 | — | — | CN | claimed |
| EP-1224183-A2 | HETEROCYCLIC SODIUM/PROTON EXCHANGE INHIBITORS AND METHOD | BRISTOL-MYERS SQUIBB COMPANY (US) | 2002-07-24 | — | — | EP | claimed |
| WO-2001027107-A2 | HETEROCYCLIC SODIUM/PROTON EXCHANGE INHIBITORS AND METHOD | BRISTOL-MYERS SQUIBB COMPANY (US) | 2001-04-19 | — | — | WO | claimed |
| WO-2023076259-A1 | TRIAZOLOPYRIDAZINE COMPOUNDS USEFUL AS RAC1 INHIBITORS | REVERE PHARMACEUTICALS (US) | 2023-05-04 | — | — | WO | disclosed |
| CN-110536892-A | New bicyclic pyrazole derivative | BAYER ANIMAL HEALTH GMBH | 2019-12-03 | — | — | CN | disclosed |
| EP-2900645-B1 | HERBICIDAL AND FUNGICIDAL 3-PHENYLISOXAZOLIN DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2019-08-21 | — | — | EP | disclosed |
| CN-106458878-B | 2- cyano -3- cyclopropyl -3- hydroxy-ns-thio the acrylamide derivative of aryl - | 艾格埃克斯制药有限公司 | 2018-08-31 | — | — | CN | disclosed |
| EP-3045450-B1 | INTERMEDIATE COMPOUNDS IN PROCESSES FOR PRODUCING PYRIDAZINONE COMPOUNDS | SUMITOMO CHEMICAL CO (JP) | 2018-02-07 | — | — | EP | disclosed |
| EP-0406661-A1 | Substituted 3-aminosydnonimines, process for their preparation, and their use | CASSELLA Aktiengesellschaft (DE) | 1991-01-09 | — | — | EP | disclosed |
| EP-0367036-A2 | Substituted 3-aminosydnonimines, process for their preparation and their use | CASSELLA Aktiengesellschaft (DE) | 1990-05-09 | — | — | EP | disclosed |
| EP-0327808-A1 | Substituted 3-aminosydnonimines, process for their preparation and their use | CASSELLA Aktiengesellschaft (DE) | 1989-08-16 | — | — | EP | disclosed |
| EP-0101974-B1 | THIADIAZINONES, PROCESS FOR THEIR PREPARATION AND FUNGICIDES CONTAINING THEM | BASF Aktiengesellschaft (DE) | 1986-01-02 | — | — | EP | disclosed |
| US-4496563-A | Fungicidal thiadiazinones | BASF AKTIENGESELLSCHAFT (DE) | 1985-01-29 | — | — | US | disclosed |
| EP-0101974-A1 | Thiadiazinones, process for their preparation and fungicides containing them | BASF Aktiengesellschaft (DE) | 1984-03-07 | — | — | EP | disclosed |