Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | GLA | P06280 | 3/20 | 0.67 |
| ▸ | GAA | P10253 | 3/20 | 0.67 |
| ▸ | HPGD | P15428 | 3/20 | 0.67 |
| ▸ | MEN1 | O00255 | 3/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | GFER | P55789 | 1/20 | 0.59 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.58 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.55 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.55 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.55 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.55 |
| ▸ | RAF1 | P04049 | 2/20 | 0.54 |
| ▸ | MPO | P05164 | 1/20 | 0.54 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7989834 | 0.85 | MAPK11 (0.71) | KDM4EKMT2AALDH1A1HPGDMEN1 | |
| SCHEMBL4551698 | 0.82 | KMT2A (0.57) | KDM4EKMT2AALDH1A1GLAGAA | |
| SCHEMBL4153691 | 0.81 | TGFBR1 (0.74) | KDM4EKMT2AALDH1A1GLAGAA | |
| SCHEMBL2593317 | 0.80 | KDM4E (0.91) | KDM4EKMT2AALDH1A1GLAGAA | |
| SCHEMBL29642733 | 0.80 | KDM4E (1.00) | KDM4EKMT2AALDH1A1GLAGAA | |
| SCHEMBL12462140 | 0.79 | MAPK14 (0.62) | KDM4EKMT2AALDH1A1GLAGAA | |
| SCHEMBL12152244 | 0.79 | NOX1 (0.68) | KDM4EKMT2AALDH1A1GLAGAA | |
| SCHEMBL12311036 | 0.79 | KDM4E (0.67) | KDM4EKMT2AALDH1A1GLAGAA | |
| SCHEMBL30979828 | 0.77 | MAPK13 (0.60) | KDM4EKMT2AALDH1A1GLAGAA | |
| SCHEMBL30979849 | 0.77 | MAPK13 (0.60) | KDM4EKMT2AALDH1A1GLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070259875-A1 | Triaryl substituted imidazole derivatives and taste-inhibiting uses thereof | REDPOINT BIO CORPORATION | 2007-11-08 | — | — | US | claimed |
| EP-2015638-A2 | TRIARYL SUBSTITUTED IMIDAZOLE DERIVATIVES AND TASTE-INHIBITING USES THEREOF | Redpoint Bio Corporation (US) | 2009-01-21 | — | — | EP | disclosed |
| US-20070259875-A1 | Triaryl substituted imidazole derivatives and taste-inhibiting uses thereof | REDPOINT BIO CORPORATION | 2007-11-08 | — | — | US | disclosed |
| WO-2007127479-A2 | TRIARYL SUBSTITUTED IMIDAZOLE DERIVATIVES AND TASTE-INHIBITING USES THEREOF | REDPOINT BIO CORPORATION (US) | 2007-11-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070259875-A1 | Triaryl substituted imidazole derivatives and taste-inhibiting uses thereof | TAS1R3, TAS2R1, TAS1R1 | KDM4E 3422/4885KMT2A 3144/4885ALDH1A1 407/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.