SCHEMBL4552106

SCHEMBL4552106

CC(=O)Nc1c[nH]c(NC(C)=O)n1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.44
LMNA P02545 2/20 0.42
GDA Q9Y2T3 1/20 0.41
KDM4E B2RXH2 4/20 0.41
HSP90AA1 P07900 1/20 0.40
HSP90AB1 P08238 1/20 0.40
ALDH1A1 P00352 1/20 0.38
ALOX15 P16050 1/20 0.38
HSD17B10 Q99714 1/20 0.38
PTK2 Q05397 1/20 0.38
HTR1F P30939 2/20 0.38
ADORA3 P0DMS8 5/20 0.37
ADORA1 P30542 2/20 0.37
ADORA2A P29274 2/20 0.37
MAPK8 P45983 1/20 0.37
ADORA2B P29275 1/20 0.37
GAA P10253 1/20 0.36
PIK3C3 Q8NEB9 1/20 0.36
HTR1A P08908 1/20 0.36
HTR1D P28221 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL216293 0.80 KDM4E (0.43) L3MBTL1LMNAGDAKDM4EALDH1A1
SCHEMBL19720097 0.80 L3MBTL1 (0.44) L3MBTL1LMNAKDM4EHSP90AA1HSP90AB1
SCHEMBL13449742 0.77 LMNA (0.40) L3MBTL1LMNAGDAKDM4EALDH1A1
SCHEMBL13467418 0.76 ALPL (0.40) LMNAGDAKDM4EALDH1A1ALOX15
SCHEMBL21608110 0.76 LMNA (0.39) L3MBTL1LMNAGDAKDM4EALDH1A1
SCHEMBL2780863 0.74 MAPK8 (0.40) L3MBTL1LMNAKDM4EHSP90AA1HSP90AB1
SCHEMBL27567731 0.72 ADORA3 (0.55) L3MBTL1LMNAKDM4EHSP90AA1HSP90AB1
SCHEMBL1201878 0.72 ADORA3 (0.55) L3MBTL1LMNAKDM4EALDH1A1ALOX15
SCHEMBL5347735 0.72 LMNA (0.36) L3MBTL1LMNAGDAKDM4EALDH1A1
SCHEMBL7232377 0.71 NPC1 (0.58) LMNAKDM4EALDH1A1ADORA3ADORA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7605215-B2 Process for producing olefin copolymerization catalyst and process for producing olefin copolymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-10-20 US disclosed
US-20080227937-A1 Process for Producing Olefin Copolymerization Catalyst and Process for Producing Olefin Copolymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-09-18 US disclosed