Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MGAT2 | Q10469 | 2/20 | 0.30 |
| ▸ | CTSS | P25774 | 1/20 | 0.30 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4422884 | 0.89 | FFAR1 (0.32) | FFAR1 | |
| SCHEMBL4415939 | 0.89 | FFAR1 (0.32) | FFAR1 | |
| SCHEMBL13673199 | 0.84 | ERN1 (0.33) | FFAR1 | |
| SCHEMBL13865611 | 0.83 | RARA (0.32) | — | |
| SCHEMBL4413888 | 0.83 | RARA (0.33) | FFAR1 | |
| SCHEMBL4421577 | 0.81 | PLA2G2A (0.33) | — | |
| SCHEMBL4413674 | 0.81 | CYP1A1 (0.40) | FFAR1 | |
| SCHEMBL18965020 | 0.80 | FFAR1 (0.32) | FFAR1 | |
| SCHEMBL13865551 | 0.80 | FFAR1 (0.34) | FFAR1 | |
| SCHEMBL30933437 | 0.79 | ALDH1A1 (0.40) | ALDH1A1KDM4EMEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1658351-B1 | MESOGENIC COMPOUNDS, MEDIUM FOR ELECTRO-OPTICAL DISPLAYS AND ELECTRO-OPTICAL DISPLAY | MERCK PATENT GMBH (DE) | 2009-10-28 | — | — | EP | disclosed |
| EP-1658351-B1 | MESOGENIC COMPOUNDS, MEDIUM FOR ELECTRO-OPTICAL DISPLAYS AND ELECTRO-OPTICAL DISPLAY | MERCK PATENT GMBH (DE) | 2009-10-28 | — | — | EP | disclosed |
| US-7531106-B2 | Mesogenic compounds, medium for electro-optical displays and electro-optical display | MERCK PATENT GMBH (DE) | 2009-05-12 | — | — | US | disclosed |
| US-7531106-B2 | Mesogenic compounds, medium for electro-optical displays and electro-optical display | MERCK PATENT GMBH (DE) | 2009-05-12 | — | — | US | disclosed |