Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMA1 | P23946 | 1/20 | 0.49 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.41 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.39 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3221281 | 0.90 | TMEM97 (0.53) | TMEM97SIGMAR1P2RX3KAT2BCXCR3 | |
| SCHEMBL11737352 | 0.79 | TDP1 (0.50) | TMEM97SIGMAR1LMNAL3MBTL1TSHR | |
| SCHEMBL14262278 | 0.78 | CXCR3 (0.45) | TMEM97P2RX3KAT2BCXCR3LMNA | |
| SCHEMBL3229333 | 0.77 | L3MBTL1 (0.44) | KAT2BLMNAL3MBTL1TSHRALDH1A1 | |
| SCHEMBL3859325 | 0.76 | CMA1 (0.59) | CMA1TMEM97SIGMAR1ALDH1A1CYP1A2 | |
| SCHEMBL18263581 | 0.73 | KAT2B (0.46) | SIGMAR1P2RX3KAT2BCXCR3L3MBTL1 | |
| SCHEMBL3225943 | 0.73 | HTT (0.65) | TMEM97SIGMAR1L3MBTL1CYP3A4 | |
| SCHEMBL18263490 | 0.72 | KMO (0.48) | KAT2BL3MBTL1 | |
| SCHEMBL30537992 | 0.70 | CMA1 (1.00) | CMA1LMNAL3MBTL1TSHRALDH1A1 | |
| SCHEMBL507970 | 0.70 | CMA1 (1.00) | CMA1LMNAL3MBTL1TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2125813-A2 | COMPOUNDS | Glaxo Group Limited (GB) | 2009-12-02 | — | — | EP | disclosed |
| WO-2008116815-A2 | COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2008-10-02 | — | — | WO | disclosed |