Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Acetaminophen. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.95 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.95 |
| ▸ | MAPT | P10636 | 3/20 | 0.95 |
| ▸ | MEN1 | O00255 | 3/20 | 0.95 |
| ▸ | CA12 | O43570 | 1/20 | 0.95 |
| ▸ | BRD4 | O60885 | 1/20 | 0.95 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.95 |
| ▸ | CA1 | P00915 | 1/20 | 0.95 |
| ▸ | CA2 | P00918 | 1/20 | 0.95 |
| ▸ | MB | P02144 | 1/20 | 0.95 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.95 |
| ▸ | CA3 | P07451 | 1/20 | 0.95 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.95 |
| ▸ | RARG | P13631 | 1/20 | 0.95 |
| ▸ | TSHR | P16473 | 1/20 | 0.95 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.95 |
| ▸ | CA4 | P22748 | 1/20 | 0.95 |
| ▸ | CA7 | P43166 | 1/20 | 0.95 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.95 |
| ▸ | CA9 | Q16790 | 1/20 | 0.95 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetaminophen SCHEMBL3480 | 0.98 | KMT2A (1.00) | KMT2AALDH1A1MAPTMEN1CA12 | |
| Acetaminophen SCHEMBL8937727 | 0.98 | KMT2A (1.00) | KMT2AALDH1A1MAPTMEN1CA12 | |
| Acetaminophen SCHEMBL252939 | 0.98 | KMT2A (1.00) | KMT2AALDH1A1MAPTMEN1CA12 | |
| Acetaminophen SCHEMBL8197085 | 0.95 | KMT2A (0.95) | KMT2AALDH1A1MAPTMEN1CA12 | |
| Acetaminophen SCHEMBL20541508 | 0.95 | ALDH1A1 (0.95) | KMT2AALDH1A1MAPTMEN1CA12 | |
| Acetaminophen SCHEMBL5081499 | 0.95 | KMT2A (0.95) | KMT2AALDH1A1MAPTMEN1CA12 | |
| Acetaminophen SCHEMBL31738441 | 0.95 | KMT2A (0.95) | KMT2AALDH1A1MAPTMEN1CA12 | |
| Acetaminophen SCHEMBL10325382 | 0.95 | KMT2A (0.95) | KMT2AALDH1A1MAPTMEN1CA12 | |
| Acetaminophen SCHEMBL8959271 | 0.95 | KMT2A (0.95) | KMT2AALDH1A1MAPTMEN1CA12 | |
| Acetaminophen SCHEMBL8207526 | 0.95 | KMT2A (0.95) | KMT2AALDH1A1MAPTMEN1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11464745-B2 | Solid pharmaceutical dosage formulations and processes | UCL BUSINESS PLC (GB) | 2022-10-11 | — | — | US | disclosed |
| CN-102759589-A | Method for simultaneously quantifying stilbene glucoside and salvianolic acid B in Guidansaji capsules | SHIJIAZHUANG ZANGNUO BIOLOGY INC COMPANY | 2012-10-31 | — | — | CN | disclosed |
| CN-102608250-A | Rapid detection method for Jinfangganmao granules | CHENGDE YANFENG PHARMACEUTICAL CO LTD | 2012-07-25 | — | — | CN | disclosed |
| US-7604820-B1 | Solid preparation containing chitosan powder and process for producing the same | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2009-10-20 | — | — | US | disclosed |
| EP-1203590-B1 | SOLID PREPARATIONS CONTAINING CHITOSAN POWDER AND PROCESS FOR PRODUCING THE SAME | DAINIPPON SUMITOMO PHARMA CO (JP) | 2007-07-04 | — | — | EP | disclosed |
| EP-1203590-A1 | SOLID PREPARATIONS CONTAINING CHITOSAN POWDER AND PROCESS FOR PRODUCING THE SAME | Dainippon Pharmaceutical Co., Ltd. (JP) | 2002-05-08 | — | — | EP | disclosed |