SCHEMBL4552644

SCHEMBL4552644

CC(=O)Nc1cc(NC(C)=O)nc(NC(C)=O)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.56
L3MBTL1 Q9Y468 2/20 0.54
MEN1 O00255 5/20 0.50
KMT2A Q03164 5/20 0.50
MAPT P10636 4/20 0.50
KDM4E B2RXH2 3/20 0.50
NPC1 O15118 2/20 0.50
RAB9A P51151 2/20 0.50
GLA P06280 1/20 0.50
TNNI3 P19429 1/20 0.50
TNNT2 P45379 1/20 0.50
TNNC1 P63316 1/20 0.50
RUNX1 Q01196 1/20 0.50
CBFB Q13951 1/20 0.50
ADORA3 P0DMS8 5/20 0.47
ADORA1 P30542 2/20 0.47
ADORA2B P29275 1/20 0.47
ADORA2A P29274 1/20 0.47
ALDH1A1 P00352 3/20 0.47
PABPC1 P11940 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18658437 0.82 ADORA3 (0.54) LMNAL3MBTL1MEN1KMT2AKDM4E
SCHEMBL1766001 0.80 L3MBTL1 (0.52) LMNAL3MBTL1KDM4EADORA3ADORA1
SCHEMBL1765929 0.80 L3MBTL1 (0.52) L3MBTL1ADORA3ADORA1ADORA2BADORA2A
SCHEMBL3071609 0.80 LMNA (0.71) LMNAL3MBTL1MEN1KMT2AMAPT
SCHEMBL12685297 0.77 LMNA (0.56) LMNAL3MBTL1MEN1KMT2AMAPT
SCHEMBL4552543 0.77 L3MBTL1 (0.59) LMNAL3MBTL1KDM4EADORA3ADORA1
SCHEMBL28907999 0.77 L3MBTL1 (0.48) LMNAL3MBTL1KDM4EADORA3ADORA1
SCHEMBL21728888 0.77 L3MBTL1 (0.48) LMNAL3MBTL1KDM4EADORA3ADORA1
SCHEMBL14221332 0.76 S1PR2 (0.69) LMNAL3MBTL1MEN1KMT2AMAPT
SCHEMBL16992910 0.76 LMNA (0.54) LMNAL3MBTL1MEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7605215-B2 Process for producing olefin copolymerization catalyst and process for producing olefin copolymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-10-20 US disclosed
US-20080227937-A1 Process for Producing Olefin Copolymerization Catalyst and Process for Producing Olefin Copolymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-09-18 US disclosed