Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPY4R | P50391 | 3/20 | 0.39 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 5/20 | 0.37 |
| ▸ | CA3 | P07451 | 2/20 | 0.37 |
| ▸ | CA5A | P35218 | 2/20 | 0.37 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1070699 | 1.00 | ALDH1A1 (0.41) | ALDH1A1POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL6382960 | 0.90 | NPY4R (0.42) | ALDH1A1POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL1724846 | 0.85 | FOLH1 (0.40) | POLBSMN1; SMN2MEN1KMT2ANPY4R | |
| SCHEMBL4552682 | 0.85 | FOLH1 (0.40) | POLBSMN1; SMN2MEN1KMT2ANPY4R | |
| Trifluoroacetic Acid SCHEMBL29816943 | 0.85 | NPY4R (0.43) | ALDH1A1SMN1; SMN2NPY4RC3AR1FOLH1 | |
| SCHEMBL29005731 | 0.84 | C3AR1 (0.43) | SMN1; SMN2MEN1KMT2ANPY4RC3AR1 | |
| SCHEMBL12971304 | 0.84 | C3AR1 (0.43) | SMN1; SMN2MEN1KMT2ANPY4RC3AR1 | |
| SCHEMBL31184339 | 0.84 | FOLH1 (0.39) | SMN1; SMN2MEN1KMT2ANPY4RC3AR1 | |
| Trifluoroacetic Acid SCHEMBL7438898 | 0.83 | NPY4R (0.45) | NPY4RC3AR1FOLH1CA12CA2 | |
| SCHEMBL1765043 | 0.83 | C3AR1 (0.45) | SMN1; SMN2MEN1KMT2ANPY4RC3AR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8691790-B2 | Therapy of neurological inflammatory diseases with (5'-deoxy-5'-adenosyl) cobamamide, recombinant human growth hormone, interleukins IL-1, IL-6, IL-11, epidermal growth factor, and physiotherapy | BOUCHER JAMES LAYNE (US) | 2014-04-08 | — | — | US | disclosed |
| US-20110020311-A1 | Therapy of multiple sclerosis, inflammatory neurological diseases and neurodegenerative diseases with 5'-deoxyadenosylcobalamin, growth hormone, immunomodulators, interleukins, other therapeutic agents, and physiotherapy | BOUCHER JAMES LAYNE | 2011-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110020311-A1 | Therapy of multiple sclerosis, inflammatory neurological diseases and neurodegenerative diseases with 5'-deoxyadenosylcobalamin, growth hormone, immunomodulators, interleukins, other therapeutic agents, and physiotherapy | ADA, ADORA2B, AHCY | ALDH1A1 3610/4885POLB 63/4885SMN1; SMN2 1294/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.