Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 6/20 | 0.42 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | TERT | O14746 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | FABP4 | P15090 | 2/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | PPARD | Q03181 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4552174 | 1.00 | FAAH (0.42) | FAAHSOAT1CYP1A2CYP2C19KMT2A | |
| SCHEMBL4566609 | 0.91 | FDPS (0.43) | — | |
| SCHEMBL4552694 | 0.78 | FAAH (0.51) | FAAHSOAT1CYP1A2CYP2C19KMT2A | |
| SCHEMBL4552173 | 0.78 | FAAH (0.51) | FAAHSOAT1CYP1A2CYP2C19KMT2A | |
| SCHEMBL4552690 | 0.77 | GGPS1 (0.48) | FAAHSOAT1CYP1A2CYP2C19KMT2A | |
| SCHEMBL4552171 | 0.77 | GGPS1 (0.48) | FAAHSOAT1CYP1A2CYP2C19KMT2A | |
| SCHEMBL7549129 | 0.76 | FDPS (0.44) | CYP1A2CYP2C19TP53MAPTLMNA | |
| SCHEMBL381427 | 0.71 | FAAH (0.48) | FAAHSOAT1CYP1A2CYP2C19KMT2A | |
| SCHEMBL11330186 | 0.71 | FAAH (0.48) | FAAHSOAT1CYP1A2CYP2C19KMT2A | |
| SCHEMBL117541 | 0.70 | FAAH (0.41) | FAAHSOAT1CYP1A2CYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090324704-A1 | PHOSPHATE DIESTER AMIDES | MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V. (DE) | 2009-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090324704-A1 | PHOSPHATE DIESTER AMIDES | PHOSPHO1, NAPEPLD, PLCG2 | FAAH 146/4885SOAT1 245/4885CYP1A2 2427/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.