Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GGPS1 | O95749 | 8/20 | 0.48 |
| ▸ | FDPS | P14324 | 11/20 | 0.47 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.42 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.41 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSPO | P30536 | 1/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4552171 | 1.00 | GGPS1 (0.48) | GGPS1FDPSSMPD1MEN1FAAH | |
| SCHEMBL4566606 | 0.91 | FDPS (0.56) | GGPS1FDPSSMPD1LPAR3 | |
| SCHEMBL7554692 | 0.87 | GGPS1 (0.49) | GGPS1FDPSSMPD1MEN1FAAH | |
| SCHEMBL7549125 | 0.77 | FDPS (0.55) | GGPS1FDPSSMPD1LPAR3 | |
| SCHEMBL7796960 | 0.77 | FDPS (0.55) | GGPS1FDPSSMPD1LPAR3 | |
| SCHEMBL4552174 | 0.77 | FAAH (0.42) | MEN1FAAHTP53CYP1A2CYP3A4 | |
| SCHEMBL4552697 | 0.77 | FAAH (0.42) | MEN1FAAHTP53CYP1A2CYP3A4 | |
| SCHEMBL9422099 | 0.77 | FDPS (0.53) | GGPS1FDPSSMPD1MEN1FAAH | |
| SCHEMBL3189568 | 0.76 | GGPS1 (0.46) | GGPS1FDPSSMPD1MEN1FAAH | |
| SCHEMBL12821938 | 0.76 | FDPS (0.79) | GGPS1FDPSSMPD1LPAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090324704-A1 | PHOSPHATE DIESTER AMIDES | MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V. (DE) | 2009-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090324704-A1 | PHOSPHATE DIESTER AMIDES | PHOSPHO1, NAPEPLD, PLCG2 | GGPS1 165/4885FDPS 198/4885SMPD1 108/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.