Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.43 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2233973 | 0.84 | POLB (0.58) | POLBALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL8310107 | 0.72 | ALDH1A1 (0.57) | POLBALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL7832804 | 0.72 | HDAC1 (0.57) | ALDH1A1MAPTRAB9ANPSR1MEN1 | |
| SCHEMBL14334562 | 0.71 | MAPT (0.68) | POLBALDH1A1MAPTRAB9A | |
| SCHEMBL27337917 | 0.69 | ALDH1A1 (0.47) | ALDH1A1MAPTRAB9ANPSR1MEN1 | |
| SCHEMBL13598423 | 0.68 | CHRNB2 (0.58) | POLBCHRNB2CHRNA4 | |
| SCHEMBL1645682 | 0.68 | HSD11B1 (0.60) | POLBALDH1A1MAPTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL5352144 | 0.67 | SIRT6 (0.63) | POLBALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL161236 | 0.67 | CHRNB2 (0.76) | CHRNB2CHRNA4 | |
| SCHEMBL11544331 | 0.67 | CHRNB2 (0.76) | CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2097413-A1 | 2-[(2-SUBSTITUTED)-IND0LIZIN-3-YL]-2-OXO-ACETAMIDE DERIVATIVES AS ANTIFUNGAL AGENTS | F2G Limited (GB) | 2009-09-09 | — | — | EP | disclosed |
| WO-2008062182-A1 | 2- [ (2-SUBSTITUTED) -IND0LIZIN-3-YL] -2-OXO-ACETAMIDE DERIVATIVES AS ANTIFUNGAL AGENTS | F2G LTD (GB) | 2008-05-29 | — | — | WO | disclosed |