Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 4/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 8/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 7/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MME | P08473 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26763905 | 0.83 | GAA (0.53) | ACACBNAMPTROCK2ROCK1HTT | |
| SCHEMBL34468891 | 0.81 | ACACB (0.51) | ACACBNAMPTROCK2ROCK1GSK3B | |
| SCHEMBL18281350 | 0.80 | ALDH1A1 (0.41) | ACACBNAMPTROCK2ROCK1ALDH1A1 | |
| SCHEMBL18281318 | 0.78 | THRB (0.49) | ACACBNAMPTROCK2ROCK1ALDH1A1 | |
| SCHEMBL566140 | 0.77 | ACACB (0.43) | ACACBROCK2ROCK1ALDH1A1HTT | |
| SCHEMBL1608977 | 0.77 | ROCK2 (0.47) | ACACBNAMPTROCK2ROCK1 | |
| SCHEMBL17065962 | 0.76 | MARK3 (0.42) | ACACBNAMPTROCK2ALDH1A1HTT | |
| SCHEMBL13373398 | 0.75 | MMP13 (0.45) | ACACBROCK2ROCK1ALDH1A1HTT | |
| SCHEMBL6639419 | 0.74 | NAMPT (0.46) | ACACBNAMPTROCK2ROCK1ALDH1A1 | |
| SCHEMBL1474376 | 0.74 | ACACB (0.39) | ACACBNAMPTROCK2ROCK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2040547-A1 | PESTICIDAL COMPOSITION COMPRISING A PYRIDYLETHYLBENZAMIDE DERIVATIVE AND AN INSECTICIDE COMPOUND | Bayer CropScience AG (DE) | 2009-04-01 | — | — | EP | disclosed |
| WO-2008003738-A1 | PESTICIDAL COMPOSITION COMPRISING A PYRIDYLETHYLBENZAMIDE DERIVATIVE AND AN INSECTICIDE COMPOUND | BAYER CROPSCIENCE AG (DE) | 2008-01-10 | — | — | WO | disclosed |