Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 2/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.44 |
| ▸ | CSF1R | P07333 | 1/20 | 0.44 |
| ▸ | MET | P08581 | 1/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.44 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.44 |
| ▸ | PRKACA | P17612 | 1/20 | 0.44 |
| ▸ | LTK | P29376 | 1/20 | 0.44 |
| ▸ | GRK5 | P34947 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | FLT3 | P36888 | 1/20 | 0.44 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.44 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10941801 | 0.97 | ADORA1 (0.46) | ADORA1CHEK1MAP4K4ABL1NTRK1 | |
| SCHEMBL7164275 | 0.85 | RAB9A (0.47) | ADORA1MAP4K4RAB9ANPC1KMT2A | |
| SCHEMBL6662358 | 0.81 | RAB9A (0.50) | ADORA1CHEK1MAP4K4ABL1NTRK1 | |
| SCHEMBL28414965 | 0.81 | ACHE (0.55) | ADORA1CHEK1MAP4K4ABL1NTRK1 | |
| SCHEMBL24689747 | 0.79 | ACHE (0.52) | ADORA1CHEK1MAP4K4ABL1NTRK1 | |
| SCHEMBL25631877 | 0.78 | MAOA (0.54) | ADORA1CHEK1MAP4K4ABL1NTRK1 | |
| SCHEMBL28399042 | 0.78 | ADORA1 (0.53) | ADORA1CHEK1MAP4K4ABL1NTRK1 | |
| SCHEMBL21407092 | 0.77 | ADORA1 (0.49) | ADORA1CHEK1MAP4K4ABL1NTRK1 | |
| SCHEMBL8397631 | 0.77 | ALDH1A1 (0.41) | ADORA1RAB9ANPC1KMT2AADORA2A | |
| SCHEMBL2922149 | 0.77 | RAB9A (0.52) | ADORA1CHEK1MAP4K4ABL1NTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622231-B2 | Imaging members containing intermixed polymer charge transport component layer | XEROX CORPORATION (US) | 2009-11-24 | — | — | US | disclosed |
| US-20080057426-A1 | Photoconductors | XEROX CORPORATION | 2008-03-06 | — | — | US | disclosed |