Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4555404 | 0.88 | GPR119 (0.30) | GPR119 | |
| SCHEMBL4553713 | 0.75 | GPR119 (0.32) | GPR119 | |
| SCHEMBL3623876 | 0.73 | GPR119 (0.47) | GPR119 | |
| SCHEMBL4554110 | 0.71 | — | — | |
| SCHEMBL3625467 | 0.67 | GPR119 (0.49) | GPR119 | |
| SCHEMBL2781696 | 0.63 | GPR119 (0.43) | GPR119 | |
| SCHEMBL10276049 | 0.62 | GPR119 (0.59) | GPR119 | |
| SCHEMBL4434868 | 0.60 | GPR119 (0.45) | GPR119 | |
| SCHEMBL3624026 | 0.60 | GPR119 (0.41) | GPR119 | |
| SCHEMBL789442 | 0.60 | FPR2 (0.47) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121661-A1 | BIPIPERIDINYL COMPOUNDS, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF TREATMENT | Merck & Co., Inc. (US) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008085316-A1 | BIPIPERIDINYL COMPOUNDS, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF TREATMENT | MERCK & CO., INC. (US) | 2008-07-17 | — | — | WO | disclosed |