Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4554600 | 0.88 | GPR119 (0.30) | GPR119 | |
| SCHEMBL4553713 | 0.88 | GPR119 (0.32) | GPR119 | |
| SCHEMBL4554945 | 0.83 | ROCK2 (0.30) | — | |
| SCHEMBL4554110 | 0.83 | — | — | |
| SCHEMBL3624026 | 0.74 | GPR119 (0.41) | GPR119 | |
| SCHEMBL3610712 | 0.69 | PIM1 (0.37) | — | |
| SCHEMBL4555409 | 0.66 | L3MBTL3 (0.35) | — | |
| SCHEMBL3625467 | 0.66 | GPR119 (0.49) | GPR119 | |
| SCHEMBL4554954 | 0.66 | L3MBTL3 (0.34) | — | |
| SCHEMBL4553721 | 0.65 | EGLN1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121661-A1 | BIPIPERIDINYL COMPOUNDS, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF TREATMENT | Merck & Co., Inc. (US) | 2009-11-25 | — | — | EP | claimed |
| WO-2008085316-A1 | BIPIPERIDINYL COMPOUNDS, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF TREATMENT | MERCK & CO., INC. (US) | 2008-07-17 | — | — | WO | claimed |