Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.41 |
| ▸ | HPSE | Q9Y251 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4555050 | 0.90 | MAPT (0.45) | MAPTRAB9APOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL4556337 | 0.89 | NPC1 (0.56) | RAB9APOLBALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL4555051 | 0.87 | ALDH1A1 (0.47) | MAPTRAB9APOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL4448117 | 0.83 | LMNA (0.46) | MAPTRAB9APOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL4439131 | 0.82 | HPSE (0.49) | MAPTRAB9APOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL2814428 | 0.80 | KMT2A (0.60) | MAPTRAB9APOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL4439125 | 0.80 | HPSE (0.49) | MAPTRAB9APOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL4556335 | 0.79 | NPC1 (0.58) | MAPTRAB9APOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL4556044 | 0.76 | NR1H4 (0.49) | MAPTRAB9APOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL4556081 | 0.76 | AAK1 (0.47) | MAPTALDH1A1SMN1; SMN2TP53MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2134676-A2 | NOVEL BENZAMIDE DERIVATIVES AS MODULATORS OF THE FOLLICLE STIMULATING HORMONE | Addex Pharma SA (CH) | 2009-12-23 | — | — | EP | claimed |
| WO-2008117175-A2 | NOVEL BENZAMIDE DERIVATIVES AS MODULATORS OF THE FOLLICLE STIMULATING HORMONE | ADDEX PHARMA SA (CH) | 2008-10-02 | — | — | WO | claimed |