Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4553358 | 0.81 | GPR119 (0.41) | GPR119 | |
| SCHEMBL4555039 | 0.81 | GPR119 (0.48) | GPR119 | |
| SCHEMBL4555411 | 0.80 | GPR119 (0.52) | GPR119 | |
| SCHEMBL4554614 | 0.79 | GPR119 (0.53) | GPR119 | |
| SCHEMBL4433800 | 0.77 | GPR119 (0.41) | GPR119 | |
| SCHEMBL4553607 | 0.77 | GPR119 (0.44) | GPR119 | |
| SCHEMBL4555034 | 0.76 | GPR119 (0.51) | GPR119 | |
| SCHEMBL3486102 | 0.75 | GPR119 (0.69) | GPR119 | |
| SCHEMBL5280717 | 0.75 | PDE4B (0.39) | GPR119 | |
| SCHEMBL4554044 | 0.73 | GPR119 (0.50) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121661-A1 | BIPIPERIDINYL COMPOUNDS, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF TREATMENT | Merck & Co., Inc. (US) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008085316-A1 | BIPIPERIDINYL COMPOUNDS, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF TREATMENT | MERCK & CO., INC. (US) | 2008-07-17 | — | — | WO | disclosed |