Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA4 | P22748 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MIF | P14174 | 1/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10576664 | 0.81 | L3MBTL1 (0.58) | L3MBTL1RAB9ACA12CA1CA2 | |
| SCHEMBL30772219 | 0.78 | ALDH1A1 (0.57) | L3MBTL1RAB9AKDM4ETDP1ALDH1A1 | |
| SCHEMBL11882522 | 0.78 | GAA (0.53) | CA1CA2ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL1553402 | 0.78 | CA1 (0.54) | L3MBTL1RAB9ACA12CA1CA2 | |
| SCHEMBL514580 | 0.78 | CA12 (0.54) | L3MBTL1RAB9ACA12CA1CA2 | |
| SCHEMBL29679041 | 0.78 | CA12 (0.54) | L3MBTL1RAB9ACA12CA1CA2 | |
| SCHEMBL6811036 | 0.78 | CA12 (0.54) | L3MBTL1RAB9ACA12CA1CA2 | |
| SCHEMBL11880043 | 0.77 | PTGS2 (0.61) | KDM4ETDP1ALDH1A1HTTMEN1 | |
| SCHEMBL22875810 | 0.76 | PDE4B (0.40) | L3MBTL1RAB9AKDM4ETDP1ALDH1A1 | |
| SCHEMBL1276460 | 0.76 | CA2 (0.53) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2035369-A1 | THERAPEUTIC COMPOUNDS | Fibrotech Therapeutics PTY LTD (AU) | 2009-03-18 | — | — | EP | disclosed |
| WO-2008003141-A1 | THERAPEUTIC COMPOUNDS | FIBROTECH THERAPEUTICS PTY LTD (AU) | 2008-01-10 | — | — | WO | disclosed |