Phthalic Anhydride

Phthalic Anhydride

SCHEMBL4555543

C=CC(=O)OCCO.O=C1OC(=O)c2ccccc21

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.59
THRB P10828 2/20 0.50
ALOX15 P16050 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
ALDH1A1 P00352 7/20 0.42
TP53 P04637 3/20 0.42
HIF1A Q16665 3/20 0.42
CYP3A4 P08684 2/20 0.42
HSD17B10 Q99714 2/20 0.42
TYMS P04818 1/20 0.41
HPGD P15428 1/20 0.39
KMT2A Q03164 2/20 0.38
GLA P06280 1/20 0.38
NPSR1 Q6W5P4 1/20 0.36
MEN1 O00255 1/20 0.36
MAPK1 P28482 2/20 0.36
SMN1; SMN2 Q16637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phthalic Anhydride SCHEMBL2007911 0.91 TSHR (0.53) TSHRTHRBALOX15TDP1ALDH1A1
Phthalic Anhydride SCHEMBL28071869 0.83 ALDH1A1 (0.55) TSHRTHRBALOX15TDP1ALDH1A1
SCHEMBL8848296 0.79 TSHR (0.61) TSHRTHRBALDH1A1TP53HIF1A
Benzene SCHEMBL11756759 0.79 TSHR (0.86) TSHRTHRBALDH1A1TP53HIF1A
Phthalic Anhydride SCHEMBL5378960 0.79 TSHR (0.49) TSHRTHRBALOX15TDP1ALDH1A1
2-Phenylphenol SCHEMBL17627907 0.79 TSHR (0.56) TSHRTHRBALDH1A1TP53HIF1A
Maleic Anhydride SCHEMBL10803750 0.79 TSHR (0.66) TSHRTHRBALDH1A1TP53HIF1A
SCHEMBL28222206 0.79 TSHR (0.66) TSHRTHRBALDH1A1TP53HIF1A
Phthalic Acid SCHEMBL301414 0.78 TSHR (0.63) TSHRTHRBALOX15ALDH1A1TP53
SCHEMBL7194597 0.78 THRB (0.66) TSHRTHRBALDH1A1TP53HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1189994-B1 OIL SOLUBLE RADIATION CURABLE METAL-CONTAINING COMPOUNDS AND COMPOSITIONS SARTOMER CO INC (US) 2009-03-18 EP disclosed
US-6399672-B1 OIL SOLUBLE UNSATURATED COMPOUNDS AND PHOTOINITIATORS SARTOMER TECHNOLOGIES CO., INC. 2002-06-04 US disclosed
EP-1189994-A2 OIL SOLUBLE RADIATION CURABLE METAL-CONTAINING COMPOUNDS AND COMPOSITIONS SARTOMER COMPANY, INC. (US) 2002-03-27 EP disclosed
WO-2000075241-A2 OIL SOLUBLE RADIATION CURABLE METAL-CONTAINING COMPOUNDS AND COMPOSITIONS SARTOMER COMPANY, INC. (US) 2000-12-14 WO disclosed